Influence of IFNα-2b and BCG on the release of TNF and IL-1 by Kupffer cells in rats with hepatoma
被引量：7
Influence of IFNα-2b and BCG on the release of TNF and IL-1 by Kupffer cells in rats with hepatoma
摘要
INTRODUCTIONKupffer cells are residential macrophages in the liver ,which play a critical role in the maintenance of normal liver function and in immunal surveilance of hepatocellular carcinoma (HCC) and other cancers[1].The biological immune modulants have cancers[2].In our previous studies ,the combined use of biological immune modulants showed better dffects .
作者
Xian Yong Bai~1 Xiu Hong Jia~2 Ling Zhong Cheng~3 Yun Di Gu~3 ~1Department of Histology and Embryology,Binzhou Medical College,Binzhou 256603,Shandong Province,China ~2Departrnent of Pediatrics,Binzhou Medical College,Binzhou 256603,Shandong Province,China ~3Department of Histology and Embryology,Shanghai Medical University,Shanghai 200032,ChinaDr.Xian Yong Bai graduated from the Shanghai Medical University as a postgraduate in 1995,Professor of Histology and Embryology,specialized in hepatic tumor immunology,having 36 papers published.
基金
Supported by the National Natural Science Foundation of China,No.39270379
二级参考文献6
-
1韩德五.肝功能衰竭发病机制的研究─—肠源性内毒素血症假说[J].肝脏病杂志,1995,3(3):134-137. 被引量：111
-
2陈贤明,韩德五,许瑞令,尹镭,赵元昌,梁振昌.内毒素对实验性急性肝功能不全的作用[J].中国病理生理杂志,1989,5(3):164-168. 被引量：8
-
3邢桦云 韩德五 等.内毒素对实验性肝功能不全的作用[J].中国病理生理杂志,1986,2:147-147.
-
4李平 朱无难 等.血浆、尿液、脑脊液、腹水及生物制品中微量内毒素的定量检测法-鲎变形细胞裂解物改良基质显色法[J].上海免疫学杂志,1985,5:39-42.
-
5王新 许才绂 等.TNFα，IL-6和IL-8与慢性肝病的关系[J].中华肝脏病杂志,1994,2:71-74.
-
6朱海轸,阮幼冰,武忠弼,SIvankovic.Kupffer细胞在实验性肝癌形成中的作用[J].中华病理学杂志,1998,27(2):102-104. 被引量：6
共引文献83
-
1梅爱敏,宋立刚,王瑞婷,张淑慧.双歧三联活菌辅助治疗肝硬化肠源性内毒素血症[J].中国医院药学杂志,2005,25(1):28-30. 被引量：14
-
2崔晓楠,侯力,刘基巍,凌茂英.DIFFERENT EFFECT OF MOUSE HEPATOCARCINOMA CELLS WITH DIFFERENT METASTATIC POTENTIAL ON HOST IMMUNE SYSTEM[J].Chinese Journal of Cancer Research,2002,14(3):175-178.
-
3Xiao-Hui Si Lian-Jun Yang Research Institute of Stomatology,the Ninth People’s Hospital,Shanghai Second Medical University,Shanghai 200011,ChinaDepartment of Pathology,Fourth Military Medical University,Xi’an 710033,Shaanxi Province,China.Extraction and purification of TGFβ and its effect on the induction of apoptosis of hepatocytes[J].World Journal of Gastroenterology,2001,7(4):527-531. 被引量：15
-
4Li Hou Ying Li Yong-Hua Jia Bo Wang Yi Xin Mao-Ying Ling Shen Lü Department of Pathology,Dalian Medical University,Dalian 116027,Liaoning Province,ChinaDepartment of Biochemistry,Dalian Medical University,Dalian 116027,Liaoning Province,China.Molecular mechanism about lymphogenous metastasis of hepatocarcinoma cells in mice[J].World Journal of Gastroenterology,2001,7(4):532-536. 被引量：47
-
5Zheng-Xu Wang~1 Gui-Fang Hu~1 Hong-Yang Wang~2 Meng-Chao Wu~2 1 Department of General Surgery,Chinese PEA General Hospital of Lanzhou Military Command,Lanzhou 730050,Gansu Province,China2 Eastern Hepatobilliary Surgical Hospital,Second Military Medical University,Shanghai 200438,China.Expression of liver cancer associated gene HCCA3[J].World Journal of Gastroenterology,2001,7(6):821-825. 被引量：9
-
6Hu-Yi Feng,Yu-Jun Shi,Chuan-Xin Wu,Sheng-Wei Li,Chang-An Liu,Jian-Ping Gong the Department of General Surgrery, Second College of Clinical Medicine & Second Affiliated Hospital, Chongqing University of Medical Sciences, Chongqing 400010, China.Mononuclear macrophages in pathogenesis of acute lung injury during acute obstructive cholangitis[J].Hepatobiliary & Pancreatic Diseases International,2002,1(4):587-591. 被引量：2
-
7林健玲,郭淑英,胡少兰.重症肝炎的彩色多普勒特征及其临床意义探讨[J].中国超声诊断杂志,2004,5(10):751-754. 被引量：2
-
8赵龙凤,王勤英,于俊岩,韩德五.内毒素对慢性肝病患者白细胞介素-2及T细胞亚群的影响[J].中华传染病杂志,2004,22(4):263-264. 被引量：11
-
9张美华,贾林.肝性脑病患者肠道微生态改变及微生态治疗[J].世界华人消化杂志,2004,12(9):2159-2161. 被引量：12
-
10邱荣元,黄吉忠,张静初,彭汉光.阴黄证内毒素水平的实验研究[J].安徽中医学院学报,2004,23(6):30-32. 被引量：3
同被引文献51
-
1Rong Qian Wu,Ying Xin Xu,Xu Hua Song,Li Jun Chen,Xian Jun Meng Institute of Surgical Research, General Hospital of PLA, Beijing 100853, China.Adhesion molecule and proinflammatory cytokine gene expression in hepatic sinusoidal endothelial cells following cecal ligation and puncture[J].World Journal of Gastroenterology,2001,7(1):128-130. 被引量：10
-
2Yong Ping Du1,Yue Ping Zhang2,Shou Chuan Wang3,Jian Shi1,Shao Hua Wu1,1.Department of Traditional Chinese Medicine. Xijing Hospital, theFourth Military Medical University. Xi an 7101132, Shaanxi Province,China 2.Department of Pediatrics. Xijing Hospital, the Fourth Military MedicalUniversity. Xi’an 710032. Shaanxi Province. China 3.Department of Pediatrics. Nanjing University of Traditional ChineseMedicine, Nanjing71011?l, Jiangsu Province. China.Function and regulation of cholecystokinin-octapeptide, β-endorphin and gastrin in anorexic infantile rats treated with ErBao Granules[J].World Journal of Gastroenterology,2001,7(2):275-280. 被引量：14
-
3Harriet Gordon.Detection of alcoholic liver disease[J].World Journal of Gastroenterology,2001,7(3):297-302. 被引量：13
-
4EdwinC.Ouyang,CatherineH.Wu,CherieWalton,KittichaiPromrat,GeorgeY.Wu.Transplantation of human hepatocytes into tolerized genetically immunocompetent rats[J].World Journal of Gastroenterology,2001,7(3):324-330. 被引量：23
-
5Guo Liang Zhang Ye Hong Wang Hui Ling Teng Zhi Bin Lin Department of Pharmacology,School of Basic Medical Sciences,Beijing University,Beijiog 100083,ChinaDr.Guo Liang Zhang graduated from Xinxiang Medical College in 1982,got Ph.D.at Nagoya City University Medical School,Japan in 1994,finished postdoctoral research at Beijing Medical Univcrsity in 1996,now an associate professor of pharmacology,specialized in hepatic pharmacology,having 15 papers published..Effects of aminoguanidine on nitric oxide production induced by inflammatory cytokines and endotoxin in cultured rat hepatocytes[J].World Journal of Gastroenterology,2001,7(3):331-334. 被引量：20
-
6Shuang Ping Guo~1 Wen Liang Wang~1 Yu Qiang Zhai~2 Yi Ling Zhao~1 ~1Department of Pathology,Xijing Hospital of the Fourth Military Medical University,Xi’an,China ~2Department of Urology,the Central Hospital of Xi’an,China.Expression of nuclear factor-KB in hepatocellular carcinoma and its relation with the X protein of hepatitis B virus[J].World Journal of Gastroenterology,2001,7(3):340-344. 被引量：55
-
7Qing He Nie Yong Qian Cheng Yu Mei Xie Yong Xing Zhou Yi Zhan Cao The Center of Infectious Disease Diagnosis and Treatment of PLA,Tangdu Hospital,Forth Military Medical University,Xi’an 710038,Shaanxi Province,ChinaDr,Qing He Nie graduated from Qinghai Medical College as a doctor in 1983,got master degree at Beijing 302 Army Hospital in 1993,got doctor degree at the Third Military Medical University in 1998,engaged in postdoctoral research at the Fourth Military Medical University from 1998 to 2000,now an associate professor,specialized in clinical and experimental research of infectious diseases,had more than 90 papers published,coauthor of ten books,first author of one book..Inhibiting effect of antisense oligonucleotides phosphorthioate on gene expression of TIMP-1 in rat liver fibrosis[J].World Journal of Gastroenterology,2001,7(3):363-369. 被引量：73
-
8Ji Lin Cheng Bao Ling Liu Yi Zhang Wen Bin Tong Zheng Yan Bai Fang Feng Institute of Hepatology,Peoples Hospital,Medical Center of Beijing University,Beijing 10(X)44,China.Hepatitis C virus in human B lymphocytes transformed by Epstein-Barr virus in vitro by in situ reverse transcriptase-polymerase chain reaction[J].World Journal of Gastroenterology,2001,7(3):370-375. 被引量：11
-
9Lin Zhuang Jing You Bao Zhang Tang Su Ying Ding Kui Hua Yan Dan Peng Yan Mei Zhang Lu Zhang ~1Department of Hepatology,Kunming Third Municipal Peoples Hospital,Kunming 650041,Yunnan Province,China ~2Department of Infectious Diseases,The First Affiliated Hospital of Kunming Medical College,Kunming 650032,Yunnan Province,China.Preliminary results of Thymosin-a1 versus interferon-α treatment in patients with HBeAg negative and serum HBV DNA positive chronic hepatitis B[J].World Journal of Gastroenterology,2001,7(3):407-410. 被引量：22
-
10Jing You Lin Zhuang Bao Zhang Tang Wei Bo Yang Su Ying Ding Wu Li Rong Xue Wu Hong Li Zhang Yan Mei Zhang Shao Ming Yan Lu Zhang ~1Department of Infectious Diseases,The First Affiliated Hospital of Kunming Medical College,Kunming 650032,Yunnan Province,China ~2Departrnent of Hepatology,Kunming Third Municipal People’s Hospital,Kunming 650041,Yunnan Province,China.A randomized controlled clinical trial on the treatment of Thymosin-a1 versus interferon-α in patients with hepatitis B[J].World Journal of Gastroenterology,2001,7(3):411-414. 被引量：48
引证文献7
-
1Yi-Ling Ling~1 Ai-Hong Meng~1 Xiao-Yun Zhao~1 Bao-En Shan~2 Jun-Lan Zhang~1 Xiao-Peng Zhang~3 1 Department of Pathophysiology,Hebei Medical University,Shijiazhuang 050017,Hebei Province,China2 Research Center of Fourth Hospital,Hebei Medical University,Shijiazhuang 050000,Hebei Province,China3 Department of Chest Surgery of Hebei Provincial People’s Hospital,Shijiazhuang 050000,Hebei Province,China.Effect of cholecystokinin on cytokines during endotoxic shock in rats[J].World Journal of Gastroenterology,2001,7(5):667-671. 被引量：31
-
2张森,万德森,潘志忠,温冠媚,李华山.大蒜油对枯否氏细胞分泌白介素18的影响[J].中国免疫学杂志,2005,21(2):116-117. 被引量：3
-
3赵会民,张森,高枫.癌胚抗原受体:结直肠癌肝转移研究新动向[J].中国普通外科杂志,2009,18(10):1072-1075. 被引量：5
-
4赵荣荣,韩东,牛作兴,刘波.成人原发性纵隔恶性黑色素瘤1例报道[J].肿瘤防治研究,2013,40(9):912-913. 被引量：1
-
5Guo-Liang Zhang Ye-Hong Wang Wei Ni Hui-Ling Teng Zhi-Bin Lin Department of Pharmacology,School of Basic Medical Sciences,Beijing University,Beijing 100083,China.Hepatoprotective role of ganoderma lucidum polysaccharide against BCG-induced immune liver injury in mice[J].World Journal of Gastroenterology,2002,8(4):728-733. 被引量：47
-
6Jian-PingGong,Chuan-XinWu.Intestinal damage mediated by Kupffer cells in rats with endotoxemia[J].World Journal of Gastroenterology,2002,8(5):923-927. 被引量：15
-
7Li-LiDai,Jian-PingGong,Guo-QingZuo,Chuan-XinWu,Yu-JunShi,Xu-HongLi,YongPeng,WuDeng,Sheng-WeiLi,chang-AnLiu.Synthesis of endotoxin receptor CD14 protein in Kupffer cells and its role in alcohol-induced liver disease[J].World Journal of Gastroenterology,2003,9(3):622-626. 被引量：20
二级引证文献121
-
1徐金锴,黎一鸣,陆宏伟.肝动脉桥式转流对再灌注早期犬移植肝CD14表达及肝损伤的影响[J].陕西医学杂志,2008,37(10):1278-1280.
-
2Zhang, Jian-Xin,Dang, Sheng-Chun,Zhang, Yong,Sha, Xin,Zhang, Li-Rong,Wei, Chuan-She,Chen, Min,Jiang, De-Li.MRI shows clodronate-liposomes attenuating liver injury in rats with severe acute pancreatitis[J].Hepatobiliary & Pancreatic Diseases International,2010,9(2):192-200. 被引量：5
-
3Zi-Kai Wang,Jian-Guo Xiao,Xue-Fei Huang,Yi-Chun Gong,Wen Li.Effect of biliary drainage on inducible nitric oxide synthase, CD14 and TGR5 expression in obstructive jaundice rats[J].World Journal of Gastroenterology,2013,19(15):2319-2330. 被引量：11
-
4彭勇,龚建平,刘长安,李生伟,刘海忠,李寿柏.肝移植缺血再灌注后Kupffer细胞CD14的表达机制[J].世界华人消化杂志,2004,12(6):1333-1336. 被引量：3
-
5Xin-LiHuang,Yi-LingLing,Yi-QunLing,Jun-LinZhou,YanLiu,Qiu-HongWang.Heme oxygenase-1 in cholecystokinin-octapeptipe attenuated injury of pulmonary artery smooth muscle cells induced by lipopolysaccharide and its signal transduction mechanism[J].World Journal of Gastroenterology,2004,10(12):1789-1794. 被引量：7
-
6葛金芳,李俊,吕雄文,金涌,姚宏伟,张磊,彭磊.脂多糖联合卡介苗诱发大鼠慢性支气管炎模型的构建[J].中国药理学通报,2004,20(7):830-834. 被引量：13
-
7李淑瑾,姚玉霞,朱桂军,凌亦凌,丛斌.CCK-8抑制LPS诱导大鼠肺间质巨噬细胞TNF-α转录及NF-κB活性[J].中国病理生理杂志,2004,20(8):1335-1339. 被引量：17
-
8郝洪升,邢全台,陈建,李延青,赵幼安,袁孟彪.乙醇慢性摄入对大鼠肝组织细胞因子TGF-β、TNF-α mRNA表达的影响[J].山东大学学报（医学版）,2003,41(6):621-623.
-
9薛永志,章国良,步秀云,王昕,李丹.抑制NO诱生对BCG免疫性肝损伤中CYP1A2表达的影响[J].世界华人消化杂志,2004,12(8):1849-1852. 被引量：5
-
10薛永志,章国良,步秀云,李丹,王昕.免疫性肝损伤中一氧化氮诱生对CYP2E1表达及代谢活性的影响[J].世界华人消化杂志,2004,12(8):1973-1976. 被引量：4
-
1周槐娜,熊江琴,黄捷平.雷贝拉唑阶梯停药疗法对十二指肠球部溃疡近期及远期疗效的初步观察[J].南昌大学学报（医学版）,2011,51(6):52-54. 被引量：3
-
2LIVER AND BILIARY SYSTEM[J].China Medical Abstracts(Internal Medicine),2001,18(3):155-162.
-
3邓彩虹,刘俊,丁震,邹标,钱伟.Treg及IL-4对重症急性胰腺炎时枯否细胞M2极化状态的调节作用[J].胃肠病学和肝病学杂志,2014,23(9):1079-1085. 被引量：2
-
4周文红,胡国龄.γ-干扰素治疗肝纤维化近况[J].中西医结合肝病杂志,2001,11(4):249-251. 被引量：2
-
5Xiang Qian Huang Department of Gastroenterology,General Hospital of Tianjin Medical University,Tianjin 300052,China.Helicobacter pylori infection and gastrointestina hormones:a review[J].World Journal of Gastroenterology,2000,6(6):783-788. 被引量：10
-
6崔晓红,潘卫,戚中田,宋燕斌,印凯,张晓华,陈汉,吴孟超.Genotyping of hepatitis C virus in patients with hepatocellular carcino Ma[J].Journal of Medical Colleges of PLA(China),1995,10(4):274-276.
-
7LIVER AND BILIARY SYSTEM[J].China Medical Abstracts(Internal Medicine),1995,12(3):173-179.
-
8周天智,何堃,龚建平.Kupffer细胞与肝脏脂质代谢紊乱的研究进展[J].世界华人消化杂志,2015,23(13):2071-2076. 被引量：1
-
9朱明华,段凌浔,戴益民,詹熔洲.Significance and identification of p53 response element binding sequence in the genome of hepatitis B virus[J].Journal of Medical Colleges of PLA(China),1998,13(4):235-240.
-
10LIVER AND BILIARY SYSTEM[J].China Medical Abstracts(Internal Medicine),1995,12(2):99-104.
