摘要
遗传学研究证实遗传因素在前列腺癌的发展过程中具有一定的作用。同时,一些病例对照研究与基于人群的队列研究也提示前列腺癌具有复杂的遗传流行病学的特征。文章分析了流行病学暴露因素及易感基因与前列腺癌的关系,并就国内外前列腺癌遗传流行病学方面的研究现状以及今后研究的发展方向作一综述。
Many genetic researches have suggested that genetic factor plays an important role in the development of prostate cancer.Meanwhile,some case-control studies and population-based cohort studies have also revealed the complex genetic epidemiology characters of prostate cancer.This paper not only analyses the relationship between epidemic exposure factors,susceptible genes and prostate cancer,but also points out the present status of genetic epidemiology of prostate cancer and the prospects of research in this aspect.
出处
《上海交通大学学报（医学版）》
CAS
CSCD
北大核心
2011年第5期672-675,共4页
Journal of Shanghai Jiao tong University:Medical Science
关键词
前列腺癌
易感基因
全基因组关联研究
单核苷酸多态性
遗传流行病学
prostate cancer
susceptible gene
genome-wide association study
single nucleotide polymorphisms
genetic epidemiology
