摘要
目的体重指数(body mass index,BMI)是衡量人体胖瘦程度的有效指标,脂肪肝与肥胖、糖尿病等代谢综合征密切相关。文中旨在探讨脂肪肝患者BMI与血脂、肝酶及胰岛素抵抗(insulin resistance,IR)的关系及意义。方法对B超诊断为脂肪肝的患者测量体重、身高,空腹抽静脉血检测血脂、肝酶、血糖、胰岛素并进行统计分析。结果脂肪肝患者体重正常、超重、肥胖组丙氨酸氨基转移酶(alanine aminotransferase,ALT)、天门冬氨酸氨基转移酶(aspartate aminotransferase,AST)、γ-谷氨酰转移酶(gamma-glutamyl,γ-GT)、胆固醇(total cholesterol,TCHO)、三酰甘油(triglycerides,TG)、IR、年龄均高于BMI正常无脂肪肝组(P<0.01);女性脂肪肝患者超重、肥胖组年龄高于BMI正常组(P<0.01),ALT值高于BMI正常组(P<0.05),但AST、γ-GT无统计学差异;男性脂肪肝患者肥胖组ALT、AST、γ-GT值高于BMI正常组(P<0.05);体重正常、超重、肥胖脂肪肝组TG、IR值分别高于相同BMI无脂肪肝组(P<0.05),IR、TG值随BMI增加增高。结论脂肪肝患者存在明显的高TG血症、胰岛素抵抗及肝酶异常,与BMI密切相关。
Objective Body mass index(BMI) is an effective index of obesity.The fatty liver disease is closely related with metabolic syndrome including obesity and diabetes.This paper is to study the relationship among BMI,alanine aminotransferase(ALT),aspartate aminotransferase(AST),gamma-glutamyl transpeptidase(γ-GT) and insulin resistance(IR) in the fatty liver disease.Methods Detected the height,weight,serum lipid,ALT,AST,γ-GT,Glucose and serum insulin in the fatty liver patients by measured with color ultrasonography.Results The ages in different BMI liver fatty disease patients older than that in the control group.The age and ALT in the female liver fatty disease patients of the overweight and obesity groups were higher than that in the female control group with liver fatty disease.AST,γ-GT in the female liver fatty disease patients had no significance among the different BMI groups.The ALT,AST and γ-GT in the male liver fatty disease patients of obesity group were higher than that in the male control group with liver fatty disease.The triglycerides(TG) and IR in the different BMI groups with liver fatty disease were respectively higher than the different BMI groups with no liver fatty disease.The IR and TG were increased as the BMI added. Conclusion The results suggested that the fatty liver disease patients had hypertriglyceridema,IR and abnormal liver enzymes,which was related with BMI.
出处
《医学研究生学报》
CAS
2011年第8期843-846,共4页
Journal of Medical Postgraduates
关键词
脂肪肝
体重指数
胰岛素抵抗
血脂
丙氨酸氨基酶
Fatty liver disease
Body mass index
Insulin resisitance
Serum lipid
Alanine aminotransferase
