摘要
目的探讨滇南小耳猪同种原位心肺联合移植手术麻醉管理的有效方法.方法 2009年1月至2010年3月对14只实验用封闭群滇南小耳猪进行心肺联合移植的实验研究.基础麻醉下插管静吸复合麻醉维持,常规体外循环下实施心肺联合移植手术,行多指标监测和临床观察.结果麻醉过程平稳,供心保护好,7例手术成功,6例成功复跳,获得短期存活,达到研究目的.结论合理选择麻醉方法和药物,及时发现并处理围术期常见并发症,减轻再灌注损伤和积极保护心肺功能是成功进行小耳猪原位心肺联合移植手术麻醉的关键.
Objective To explore an effective method for anesthesia management on Yunnan miniature pigs with orthotopic heart lung transplantation.Methods 14 Yunnan miniature pigs were researched from 2009 January to 2010 March.In the anesthesia management,the combined heart and lung transplantation operation was taken under the conventional extracorporeal circulation,multiple clinical indexex were monitored and observed.Results Anesthesia process was stable,the donor heart was kept good.7 cases were operated successfully,in which 6 cases were resuscitated successfully,had short-term survival and achieved the research goal.Conclusion Rational choice of anesthetic methods and drugs,timely detection and treatment of perioperative complications,actively alleviating reperfusion injury and protecting the heart-lung function are key factors for successful anesthesia management on Yunnan miniature pigs with orthotopic heart lung transplantation.
出处
《昆明医科大学学报》
CAS
2012年第4期30-34,共5页
Journal of Kunming Medical University
基金
云南省科技厅科技计划项目(2007CA005)
关键词
心肺联合移植
猪
麻醉管理
Combined heart-lung transplantation
Procine
Anesthesia management
