期刊文献+

BDNF Va166Met多态性在抑郁障碍中的作用

下载PDF
导出
摘要 近5年来,随着对抑郁障碍研究的深入,新的发现如海马神经发生异常机制的明确、脑源性神经营养因子(brain-derivedneurotrophic factor,BDNF)在抑郁障碍中的保护作用,以及抑郁症患者脑功能连接异常等,均证实神经网络改变是抑郁发生的早期事件。
作者 罗本燕
出处 《中国卒中杂志》 2012年第10期755-759,共5页 Chinese Journal of Stroke
  • 相关文献

参考文献41

  • 1Masi G,Brovedani P. The hippocampus,neurotrophic factors and depression:possible implications for the pharmacotherapy of depression[J].Cns Drugs,2011.913-931.
  • 2Han Q,Li B,Feng H. The promotion of cerebral ischemia recovery in rats by laminin-binding BDNF[J].Biomaterials,2011.5077-5085.
  • 3Egan MF,Kojima M,Callicott JH. The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memor y and hippocampal function[J].Cell,2003.257-269.
  • 4Bath KG,Jing DQ,Dincheva I. BDNF Val66Met impairs fluoxetine-induced enhancement of adult hippocampus plasticity[J].Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology,2012.1297-1304.
  • 5Perea CS,Paternina AC,Gomez Y. Negative affectivity moderated by BDNF and stress response[J].Journal of Affective Disorders,2012.767-774.
  • 6van Oostrom I,Franke B,Rijpkema M. Interaction between BDNF Val66Met and childhood stressful life events is associated to affective memory bias in men but not women[J].Biological Psychiatry,2012.214-219.
  • 7Hayden EP,Klein DN,Dougherty LR. The role of brain-derived neurotrophic factor genotype,parental depression,and relationship discord in predicting early-emerging negative emotionality[J].Psychological Science,2010.1678-1685.
  • 8Elzinga BM,Molendijk ML,Oude Voshaar RC. The impact of childhood abuse and recent stress on serum brain-derived neurotrophic factor and the moderating role of BDNF Val66Met[J].Psychopharmacology(Berlin),2011.319-328.
  • 9Pregelj P,Nedic G,Paska AV. The association bet ween brain-der ived neu rot rophic factor polymorphism(BDNF Val66Met)and suicide[J].Journal of Affective Disorders,2011.287-290.
  • 10Schenkel LC,Segal J,Becker JA. The BDNF Val66Met polymorphism is an independent risk factor for high lethality in suicide attempts of depressed patients[J].Progress in Neuro-Psychopharmacology & Biological Psychiatry,2010.940-944.

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部