摘要
目的探讨超声双重造影对直肠癌大体分型的评估价值。方法 71例直肠癌患者术前行直肠腔内灌注胃肠声学造影剂和静脉注射微泡造影剂,观察肿瘤大体形态,根据形态将直肠癌分为隆起型、溃疡型、浸润型3个大体类型,单纯灌注造影与双重造影分型分别与术后病理分型对照。术后分析肿瘤大体类型与TN分期之间的关系。结果灌注超声造影判断直肠癌大体分型的准确率为73.2%(52/71),超声双重造影判断直肠癌大体分型的准确率为88.7%(63/71)。超声双重造影判断直肠癌分型准确率高于灌注超声造影,两者间差异有统计学意义(χ2=5.534,P<0.05)。隆起型直肠癌肠壁浸润深度以T1、T2和T3多见,溃疡型和浸润型直肠癌以T2、T3和T4多见,隆起型直肠癌淋巴结分期以N0和N1为主,溃疡型和浸润型直肠癌以N1和N2为主。隆起型与溃疡型和浸润型直肠癌肠壁浸润深度T分期和区域淋巴结转移N分期情况比较,差异均有统计学意义(χ2=12.322、6.733,P均<0.05)。结论超声双重造影能较准确地评估直肠癌的大体类型。隆起型直肠癌对肠壁的侵袭能力和淋巴结转移能力相对较弱,溃疡型和浸润型则相对较强。
Objective To investigate the clinical value of double contrast-enhanced ultrasonography (DCUS) in the macroscopic classification of rectal carcinoma. Methods Seventy-one patients with rectal carcinoma were examined by ultrasound after intrarectal infusion and intravenous bolus injection of SonoVue preoperatively. And three types were divided according to the shape of the tumor:protruding type, ulcerative type and invasive type. After surgery, DCUS and perfusion contrast-enhanced ultrasonography (PCUS) were compared with final pathologic results respectively, and the relationship between general tumor type and TN staging were analyzed.Results The accuracy of DCUS [88.7%(63/71) ] in macroscopic classification of rectal carcinoma was significantly higher than that of PCUS [73.2%(52/71) ](χ2=5.534,P<0.05). For the invasion depth into the intestinal wall, the protruding type was mainly in T1, T2 and T3 stages while ulcerative and invasive type in T2, T3 and T4 stages (χ2=12.322, P<0.05 ). For the stage of lymph node, the protruding type was mainly in N0 and N1 while ulcerative and invasive type in N1 and N2(χ2=6.733,P < 0.05 ). Conclusions DCUS, with its high accuracy, is a new valuable method for macroscopic classification of rectal carcinoma.In the aspect of intestinal wall invasion and the lymph node, protruding type is less severe than ulcerative type and invasive type.
出处
《中华医学超声杂志（电子版）》
2013年第9期746-750,共5页
Chinese Journal of Medical Ultrasound(Electronic Edition)
基金
浙江省卫生厅医药卫生科技项目(2012KYB014)
关键词
超声检查
造影剂
直肠肿瘤
Ultrasonography
Contrast media
Rectal neoplasms
