摘要
目的:研究痹痛贴提取挥发油的水煎液除杂工艺。方法:采用乙醇沉淀法,以初始药液质量浓度、药液含乙醇浓度为考察因素,以浸膏收率和阿魏酸的含量为评价指标,通过正交设计表来安排实验。结果:初始药液质量浓度为1.0～1.10g·mL-1,乙醇醇沉浓度为70%为最佳浓缩工艺,所得醇浸膏收率为15.69%,阿魏酸含量为2.49mg。结论:所建立的浓缩工艺稳定、可控,重复性好。
Objective:To study the purifying technology of extract volatile oil decoction for Bitong Patch. Method:Ethanol precipitation method was used. The experiments were designed by orthogonal design table with the amount of physic liquor mass concentration and ethanol concentration as examine factors, and extractum yield and ferulic acid content as evaluation index,. Result:The initial solution concentration was 1.0～1.10 g·mL-1. The concentration of ethanol and alcohol precipitation of 70% was the preferred concentration process with 15.69% alcohol extract yield and 2.49 mg ferulic acid. Conclusion:The enrichment process is stable, controllable and repeatable.
出处
《中药与临床》
2013年第1期27-28,39,共3页
Pharmacy and Clinics of Chinese Materia Medica
关键词
除杂工艺
乙醇醇沉
浸膏收率
阿魏酸
高效液相色谱
Purifying technology
ethanol alcohol precipitation
alcohol extract yield
ferulic acid
HPLC
