摘要
结直肠癌复发转移是患者死亡的主因,早期发现肿瘤转移的证据能提高复发肿瘤的疗效。寻找结直肠癌复发转移的分子标志物是结直肠癌转化医学研究的重要内容之一。结直肠癌复发转移分子标志物转化研究的一般过程包括高通量数据处理基础上的分子标志物发掘,分子功能的鉴定,单中心小样本验证和多中心大样本的确认等四个关键步骤。
Metastasis is the major cause of the death related to colorectal cancer. Early awareness of the potential metastatic colorectal cancer brings favorable treatment outcomes. Therefore,exploring early biomarkers of colorectal cancer metastasis is the important field of translational research of colorectal cancer.The process of the translational research for the early biomarkers of metastatic colorectal cancer involves discovery,identification,verification and validation of the early biomarkers.
出处
《中华结直肠疾病电子杂志》
2013年第1期2-5,共4页
Chinese Journal of Colorectal Diseases(Electronic Edition)
关键词
结直肠癌
肿瘤转移
转化研究
分子标志物
Colorectal neoplasms
Neoplasm metastasis
Translational research
Molecular biomarker
