期刊文献+

氧化型低密度脂蛋白胆固醇与动脉粥样硬化 被引量:12

下载PDF
导出
摘要 动脉粥样硬化( atherosclerosis,AS)的形成过程极其复杂,其发病机制涉及炎性反应、脂质代谢失调及氧化应激等多种病理生理机制[1-3]。其中,低密度脂蛋白胆固醇(low density lipoprotein cholesterin,LDL-C)的氧化修饰被认为是AS形成的关键启动因素[4]。
出处 《中国医学前沿杂志(电子版)》 2012年第8期33-37,共5页 Chinese Journal of the Frontiers of Medical Science(Electronic Version)
基金 国家自然科学基金(81070171) 北京市自然科学基金(7082081) 中国高等教育博士点项目专项研究基金(20111106110013)部分资助项目
  • 相关文献

参考文献36

  • 1Ross R. The pathogenesis of atherosclerosis:a perspective for the 1990s[J].Nature,1993,(6423):801-809.
  • 2Katagiri H,Yamada T,Oka Y. Adiposity and cardiovascular disorders:disturbance of the regulatory system consisting of humoral and neuronal signals[J].Circulation Research,2007,(01):27-39.
  • 3Glass CK,Witztum JL. Atherosclerosis:the road ahead[J].Cell,2001,(04):503-516.doi:10.1016/S0092-8674(01)00238-0.
  • 4Steinberg D. Atherogenesis in perspective:hypercholesterolemia and inflammation as partners in crime[J].Nature Medicine,2002,(11):1211-1217.
  • 5Kugiyama K,Kerns SA,Morrisett JD. Impairment of endotheliumdependent arterial relaxation by lysolecithin in modified low-density lipoproteins[J].Nature,1990,(6262):160-162.
  • 6Stiko-Rahm A,Hultgardh-Nilsson A,Regnstrom J. Native and oxidized LDL enhances production of PDGF AA and the surface expression of PDGF receptors in cultured human smooth muscle cells[J].Arteriosclerosis and Thrombosis,1992,(09):1099-1109.
  • 7Yui S,Sasaki T,Miyazaki A. Induction of murine macrophage growth by modified LDLs[J].Arteriosclerosis and Thrombosis,1993,(03):331-337.
  • 8Steinberg D,Parthasarathy S,Carew TE. Beyond cholesterol.Modifications of low-density lipoprotein that increase its atherogenicity[J].New England Journal of Medicine,1989,(14):915-924.
  • 9Shoji T,Nishizawa Y,Fukumoto M. Inverse relationship between circulating oxidized low density lipoprotein (oxLDL) and antioxLDL antibody levels in healthy subjects[J].Atheroclerosis,2000,(01):171-177.
  • 10Fraley AE,Tsimikas S. Clinical applications of circulating oxidized low-density lipoprotein biomarkers in cardiovascular disease[J].Current Opinion in Lipidology,2006,(05):502-509.doi:10.1097/01.mol.0000245255.40634.b5.

同被引文献181

引证文献12

二级引证文献40

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部