摘要
目的临床观察影响颈动脉粥样硬化(carotid atherosclerosis,CAS)高血压和CAS非高血压的相关因素,分析导致高血压CAS的病因病机和血脉损伤的主要原因及发病机制,初步探索高血压CAS病因病机与血脉理论的相关性,以期用血脉理论指导高血压CAS的防治。方法选择CAS高血压患者110例,CAS非高血压患者76例,随机分为两组。观察两组在一般资料、相关危险因素、中医火热积分、血生化指标、颈部血管超声等方面的差异。结果通过两组统计分析,发现伴有高血脂病史、脑卒中病史、冠心病病史以及甘油三酯(TG)升高、空腹血糖(FBG)升高的CAS患者高血压组要高于非高血压组,差异有显著性(P<0.05)。两组在颈动脉内-中膜厚度(IMT)上差异有显著性(P<0.05)。结论高血压能促进CAS的进展,是其独立的危险因素。伴有高血压的CAS更容易罹患高脂血症、脑卒中、冠心病以及FBG异常,伴有高血压的CASIMT更大,CAS形成是一个由多种因素,长时间综合作用的结果。
Objective Clinical observing the related factors on the influence of hypertensive or not Hypertension and CAS. Analysing the pathogenesis cause of hypertension CAS andthe main cause and pathogenesis of veins damage, preliminary exploring the relevance of the etiology and pathogenesis of hypertension CAS and Veins theory, in order to use the Veins theory to control the hypertension CAS. Methods Selecting the patients of carotid atherosclerosis with hypertension 110 cases, carotid atherosclerosis with not hypertension 76 cases, divided into two groups randomly. Observing the differences of the two groups in the general datas, associated risk factors, traditional Chinese medicine hot points, blood biochemical indexes, neck vascular ultrasound such as on. Results By the statistical analysis of two groups, finding the CAS patients with high cholesterol history,history of coronary heart disease and stroke history, elevated TG, elevated FBG with hypertension group is higher than that with not hypertension group, a statistically significant difference (P<0.05). Two groups in carotid IMT has a statistically significant difference (P<0.05). Conclusion Hypertension can promote the progression of CAS, is the independent risk factor. CAS with hypertension accompanied easily hyperlipemia, cerebral stroke, coronary heart disease and impaired fasting glucose, accompanied by hypertension CAS intima-media thickness is greater, CAS is the result of the comprehensive effect of long time by a variety of factors.
出处
《中国医学前沿杂志（电子版）》
2012年第12期45-49,共5页
Chinese Journal of the Frontiers of Medical Science(Electronic Version)
关键词
高血压
颈动脉粥样硬化
火热
血脉
Hypertension
Carotid atherosclerosis
Fiery
Veins
