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比较单次负荷剂量右美托咪啶和咪唑安定注射对鼻内镜手术全麻的影响 被引量:7

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摘要 目的观察比较单次负荷剂量右美托咪啶和咪唑安定注射对鼻内镜手术全麻的影响效果。方法将60例行鼻内镜手术患者,随机分成右美托咪啶组(D组)和咪唑安定组(C组)。D组病人诱导前缓慢静脉注射右美托咪啶1μg/kg,M组诱导前静脉注射咪达唑仑2 mg。静脉注射丙泊酚和芬太尼、阿曲库铵进行全麻诱导,丙泊酚、芬太尼、阿曲库铵维持麻醉,术中观察血压、心率,根据病人的应激反应调节丙泊酚输注速度,记录维持异丙酚用量。记录插管期、术中及拔管期的血流动力学变化及苏醒拔管时间和苏醒时有无躁动。结果与C组比较,D组麻醉维持异丙酚用量明显减少(P<0.05)。苏醒时间、拔管时间无统计学意义(P>0.05)。D组术中收缩压、心率均较C组降低,苏醒时躁动明显少于C组(P<0.05)。结论静脉注射右美托咪啶,麻醉中可节省异丙酚的用量,术中血流动力学平稳,苏醒期躁动少,并具有良好的安全性。
出处 《江西医药》 CAS 2013年第3期237-239,共3页 Jiangxi Medical Journal
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