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心肌梗死后室间隔穿孔的手术治疗时机、术式改进及其效果 被引量:3

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摘要 心肌梗死后室间隔穿孔的发病率占急性心肌梗死的1%~2%,约占急性心肌梗死死亡病例的5%[1]。急性心肌梗死后室间隔穿孔是急性心肌梗死的严重并发症,如不治疗患者很快死亡。24 h之内病死率为25%,1周内病死率50%,2周内死亡65%,4周内死亡80%。仅有8%的患者可存活至1年。心肌梗死后室间隔穿孔的真正原因还不清楚,但是人们发现穿孔多发生在透壁性心肌梗死面积较大的患者,心肌梗死面积较小者少见。尽管室间隔穿孔可在急性心肌梗死后数小时到2周内发生,但大部分发生在急性心肌梗死后2~4 d。室间隔穿孔后,产生左向右分流,分流量与穿孔的大小有关。心室水平的分流导致肺循环血流量增加,体循环血流量减少,因而出现心力衰竭,严重者出现心源性休克、多器官功能衰竭。内科药物治疗,可短暂缓解病情,但大多数患者仍难免死于心力衰竭和并发症。外科手术治疗是目前唯一挽救患者生命的手段。
作者 吴树明
出处 《心血管外科杂志(电子版)》 2013年第1期8-10,共3页 Journal of Cardiovascular Surgery(Electronic Edition)
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参考文献8

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同被引文献25

  • 1王林佩,刘丽华.急性心肌梗死溶栓治疗的护理措施[J].解放军医药杂志,2010,22(S1):66-67. 被引量:1
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