期刊文献+

排卵障碍患者用来曲唑与尿促性腺激素方案促排卵对子宫内膜形态的影响的比较 被引量:3

原文传递
导出
摘要 目的:探讨排卵障碍患者用来曲唑方案与尿促性腺激素方案对子宫内膜形态的影响。方法:回顾性分析2009年1月-2011年4月我院门诊就诊的排卵障碍患者60例,共计80个促排卵周期,其中,来曲唑组34个周期,尿促性激素组46个促排卵周期。比较hCG日两组间子宫内膜厚度,形态,优势卵泡数目、排卵数及妊娠结局。结果hCG日来曲唑组子宫内膜厚度为8.700±2.6952mm,尿促性腺素组子宫内膜厚度为9.463±1.9537mm,P>0.05,差异无统计学意义,但在形态上,来曲唑组子宫内膜A、A-B型为52.9%,而尿促性腺激素组为16.5%两组间差异有统计学意义。来曲唑组平均优势卵泡个数为1.4706±1.3311,尿促性激素组为3.5217±4.0756个,两者比较,P<0.05,差异有统计学意义。结论:排卵障碍患者用来曲唑方案与尿促性腺激素方案相比并不降低周期妊娠率,且来曲唑方案有更明显的单卵泡发生率,可获得更好的子宫内膜形态。
出处 《兵团医学》 2011年第3期46-48,共3页 Journal of BingTuan Medicine
  • 相关文献

参考文献5

二级参考文献19

  • 1Casper RF. Letrozole versus clomiphene citrate: which is better for ovulation induction [J]? Fertil Steril Press, 2007, 88(4) :1-2.
  • 2The Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome [J]. Fertil Steril, 2004, 81(1):19-25.
  • 3林守清.生殖内分泌学[M].第1版.北京:人民卫生出版社,2006:627.
  • 4Begum MR, Begum A. Letrozole vs clomiphene citrate in induction of ovulation in polycystic ovarian disease (PCOD) [J]. Fertil Steril, 2006, 86(3):408.
  • 5Badawy A, Abdel I, Abulatta M. Clomiphene citrate or letrozole for ovulation induction in women with polycystic ovarian syndrome:a prospective randomized trial [J]. Fertil Steril Oline, 2007, 87(1):1-4.
  • 6Bayar U, Basaran M, Kiran S, et al. Use of an aromatase inhibitor in patients with polycystic ovary syndrome: a prospective randomized trial [J]. Fertil Steril, 2006, 86(5) :1447-1451.
  • 7Mitwally MF, Casper RF. The Aromatase inhibitor,letrozole : a promising alternative for clomiphene citrate for induction of ovulation . Curropin Obstet Gynecol,2002,14 (3) :255.
  • 8Mitwally MF, Casper RF. Use of an aromatase inhibitor for induction of ovulation in patients with an inadequate response to clomiphene citrate. Fertil Steril,2001,75 (2) :305.
  • 9Tulay MD, Mustafa MD. Comparison of the effects of letrozole and clomiphene citrate on ovalan follicles, endometrium, and hormone levels in the rat. Fertil Stefil,2003,80 (6) :1330.
  • 10Vendola K,Zheu J, Wang J, et al. Androgens promote ocyte Insulin like growth factor 1 expression and initiation of follicle development in the primate ovary. Biol Reprod, 1999,61 (2) :353.

共引文献42

同被引文献48

  • 1王丽娜,乔杰,李蓉,胡卫红.多囊卵巢综合征患者种植窗口期子宫内膜容受性的研究[J].中华妇产科杂志,2007,42(5):298-301. 被引量:10
  • 2李翠明,张清学.芳香化酶抑制剂来曲唑促排卵的研究进展[J].国外医学(计划生育.生殖健康分册),2007,26(3):125-127. 被引量:7
  • 3陈蓉,林守清.多囊卵巢综合征的临床演变[J].中国实用妇科与产科杂志,2007,23(9):727-730. 被引量:10
  • 4苏继莲,艾红,郑建淮,任娟.经阴道超声评估来曲唑对多囊卵巢综合征的治疗作用[J].生殖与避孕,2007,27(9):593-597. 被引量:7
  • 5Baruah J, Roy KK, Rahman SM, et al. Endometrial effects of letrozole and clomiphene citrate in women with polycystic ovary syndrome using spiral artery Doppler[J]. Arch Gyneeol Obstet, 2009, 279(3) :311- 314.
  • 6Imani B,Eijkemans MJ,Velde ER,et al. A nomogram to predict the probability of live birth after clomiphene citrate induction of ovulation in normogonadotropic oli- goamenorrheic infertility [J]. Fertil Steril, 2002, 77 (1):91.
  • 7Palomba S, Falbo A, Zulto F. Management strategies for ovulation induction in women with polycystic ovary syndrome and known clomifene citrate resistanceFJ:. Curt Opin Obstet Gynecol 2009,21 (6) : 465-73.
  • 8Holzer H, Casper R, Tulandi T. A new era in ovula- tion induction [J]. Fertil Steril, 2006,85 (2) : 277-284.
  • 9Haynes BP,Dowsett M, Miller WR, et al. ne phar- macology ofletrozele[J]. J Steroid Biochem Mole Bi01. 2003.87(1) :35-45.
  • 10Wallace KL, Johnson V,Sopelak V, et al. Clomi- phene citrate versus letrozole: molecular analysis of the endometrium in women with polycystic ovary syw drome [J]. Fertil Steril,2011, 96(4) : 1051-1056.

引证文献3

二级引证文献36

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部