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七叶皂苷钠对脊髓型颈椎病术后疗效的前瞻性研究

The prospective study about the Postoperative treatment effect of Sodium aescinat to cervical spondylotic myelopathy
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摘要 目的:观察七叶皂苷钠对脊髓型颈椎病术后疗效的影响。方法:将符合病例纳入标准的72例脊髓型颈椎病患者随机分成治疗A组、治疗B组和对照组。治疗A组手术前后均应用七叶皂苷钠治疗,治疗B组仅术后应用七叶皂苷钠治疗,对照组术后应用甘露醇治疗;通过JOA评分法观察三组患者第7天症状改善情况。结果:治疗组疗效明显优于对照组,差异有统计学意义(P<0.01),治疗A组的疗效高于治疗B组,差异有统计学意义(P<0.05)。结论:七叶皂苷钠对脊髓型颈椎病术后神经功能恢复具有确切的辅助疗效,且手术前后联合应用比单独术后应用效果更好。 Objective:to observe the curative effects of Sodium aescinat to cervical spondylotic myelopathy.Methods:the cases of standard correspond in 72 cases with cervical spondylotic myelopathy were randomly divided into treatment group A,group B and control group.Cases in group A were injected Sodium aescinat injection preoperation and postoperation on cervical spondylotic myelopathy;Cases in group B were injected Sodium aescinat injection only postoperation on cervical spondylotic myelopathy;Cases in group control were injected mannitol injection postoperation on cervical spondylotic myelopathy;At seven day,to observe Cases in group A,group B and control group through JOA grade.Result:the curative effect of treatment group was better than control group,the difference was statistically significant(P < 0.01),the treatment effect of the treatment group A than B,the difference was statistically significant(P < 0.05).Conclusion:Sodium aescinat to cervical spondylotic myelopathy postoperative neurological recovery has assisting effect,and surgery combined application effect is better than single postoperative applications.
作者 许辉
出处 《长沙医学院学报》 2009年第2期22-24,共3页 Journal of Changsha Medical University
关键词 七叶皂苷钠 脊髓型颈椎病 Sodium aescinat cervical spondylotic myelopathy
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