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Evaluation of directly observed treatment short courses at a secondary health institution in Ibadan,Oyo State,Southwestern Nigeria 被引量:1

Evaluation of directly observed treatment short courses at a secondary health institution in Ibadan,Oyo State,Southwestern Nigeria
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摘要 Objective:To evaluate the success rate of tuberculosis intervention programme at a specialist hospital in(?)badan,Nigeria through a retrospective study as well as carry out physicochemical evaluation of anti-tuberculous agents as a way of eliminating drug-related failure.Methods:The retrospective study involved the use of quarterly tuberculosis central register at the Government Chest Hospital,(?)badan between 1st quarter(2003)to 4th quarter(2009).Relevant data were extracted from these register with the aid of data collection forms.The basic physicochemical analyses of the drugs given to the patients were also carried out using the International Pharmacopoeia methods.Results:All the drugs examined for their physicochemical properties passed the International Pharmacopeia recommended tests.A total number of 1 260 patients enrolled at the hospital were assessed through case notes.This comprises of 59.4%males of which69.23%new cases were also males.There was a significant(P<0.05)patient enrollment across the quarters for the seven years.An overall 80.24%cure rate over the 7-period was obtained which is less than the WHO target of 85%.Cure rates were better in females than males.Failure treatment outcomes such as positive(1.51%),deaths(8.73%),defaulted(3.33%)and transferred out(5.95%)were recorded though not statistically significant(P>0.05).Failure rates in all categories were higher in males than females(P>0.05).Conclusions:More enlightenment and counseling is still required to meet up with the target for TB control. Objective:To evaluate the success rate of tuberculosis intervention programme at a specialist hospital in(?)badan,Nigeria through a retrospective study as well as carry out physicochemical evaluation of anti-tuberculous agents as a way of eliminating drug-related failure.Methods:The retrospective study involved the use of quarterly tuberculosis central register at the Government Chest Hospital,(?)badan between 1st quarter(2003)to 4th quarter(2009).Relevant data were extracted from these register with the aid of data collection forms.The basic physicochemical analyses of the drugs given to the patients were also carried out using the International Pharmacopoeia methods.Results:All the drugs examined for their physicochemical properties passed the International Pharmacopeia recommended tests.A total number of 1 260 patients enrolled at the hospital were assessed through case notes.This comprises of 59.4%males of which69.23%new cases were also males.There was a significant(P&lt;0.05)patient enrollment across the quarters for the seven years.An overall 80.24%cure rate over the 7-period was obtained which is less than the WHO target of 85%.Cure rates were better in females than males.Failure treatment outcomes such as positive(1.51%),deaths(8.73%),defaulted(3.33%)and transferred out(5.95%)were recorded though not statistically significant(P&gt;0.05).Failure rates in all categories were higher in males than females(P&gt;0.05).Conclusions:More enlightenment and counseling is still required to meet up with the target for TB control.
出处 《Asian Pacific Journal of Tropical Medicine》 SCIE CAS 2013年第12期952-959,共8页 亚太热带医药杂志(英文版)
关键词 TUBERCULOSIS DOTS therapy Success rate Anti-TB drugs PHYSICOCHEMICAL EVALUATION Tuberculosis DOTS therapy Success rate Anti-TB drugs Physicochemical evaluation
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  • 1Katherine McQuade Billingsley,Nathaniel Smith,Rhett Shirley,Loice Achieng,Philip Keiser.A quality assessment tool for tuberculosis control activities in resource limited settings[J]. Tuberculosis . 2011
  • 2Neel R Gandhi,Paul Nunn,Keertan Dheda,H Simon Schaaf,Matteo Zignol,Dick van Soolingen,Paul Jensen,Jaime Bayona.Multidrug-resistant and extensively drug-resistant tuberculosis: a threat to global control of tuberculosis[J]. The Lancet . 2010 (9728)
  • 3Douglas B. Young,Hannah P. Gideon,Robert J. Wilkinson.Eliminating latent tuberculosis[J]. Trends in Microbiology . 2009 (5)
  • 4Sarah Escott,James Newell.Don’t forget the bigger picture: The impact of societal issues on a community-based TB programme, Swaziland[J]. Journal of Health Organisation and Management . 2007 (6)
  • 5Alan D Lopez,Colin D Mathers,Majid Ezzati,Dean T Jamison,Christopher JL Murray.Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data[J]. The Lancet . 2006 (9524)
  • 6James N Newell,Sushil C Baral,Shanta B Pande,Dirgh Sing Bam,Pushpa Malla.Family-member DOTS and community DOTS for tuberculosis control in Nepal: cluster-randomised controlled trial[J]. The Lancet . 2006 (9514)
  • 7Vitoria Marco,Granich Reuben,Gilks Charles F,Gunneberg Christian,Hosseini Mehran,Were Wilson,Raviglione Mario,De Cock Kevin M.The global fight against HIV/AIDS, tuberculosis, and malaria: current status and future perspectives. American journal of clinical pathology . 2009
  • 8World Health Organization.Global tuberculosis control - surveillance, planning, financingWHO Report,2008.
  • 9Salami A K,Oluboyo P O.Management outcome of pulmonary tuberculosis: a nine year review in Ilorin. West African journal of medicine . 2003
  • 10B. Castelnuovo.A review of compliance to anti tuberculosis treatment and risk factors for defaulting treatment in Sub Saharan Africa. AFRICAN HEALTH SCIENCES . 2010

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