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86例妊娠合并甲状腺功能减退临床分析 被引量:2

Clinical Analysis of 86 Cases of Hypothyroidism with Thyroid Function in Pregnancy
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摘要 目的:探讨妊娠合并甲状腺功能减退患者的治疗方法以及妊娠结局分析。方法回顾分析2012年1月~2013年12月收治的86例妊娠合并甲状腺功能减退孕妇(甲减组)临床资料,取同期86例甲状腺功能正常孕妇作为对照组。对比分析2组资料的围生儿情况。结果甲减组妊娠期高血压、糖代谢异常、妊娠肝内胆汁淤积症、胎儿宫内窘迫发生率明显高于正常组,差异有统计学意义(P<0.05);甲减组胎儿早产、新生儿窒息、胎儿畸形发生率明显高于对照组,差异有统计学意义(P<0.05)。结论对于妊娠合并甲减患者,须及时施以甲状腺激素等相关治疗,可全面避免或降低妊娠合并症发生,并对有效改善妊娠结局具有积极意义。 Objective To explore the method of treatment of hypothyroidism during pregnancy and pregnancy outcome. Methods Comparative analysis was done for the clinical data of 86 cases of pregnancy complicated with hypothyroidism from January 2012 to December 2013 and 86 cases of pregnant women with normal thyroid function in the same period as control group. Results Hypothyroidism in pregnancy induced hypertension, abnormal glucose metabolism and intrahepatic cholestasis of pregnancy, and fetal distress was significantly higher than that in the control group (P<0.05), statistically significant. Premature birth, asphyxia of newborn, and fetal malformation rate in hypothyroidism group was significantly higher than the control group (P<0.05), statistically significant. Conclusion Patients with hypothyroidism during pregnancy should get timely thyroid hormone treatment, which can completely avoid or reduce pregnancy complications and have positive significance to improve the outcome of pregnancy.
作者 孟晓燕 金蕾
出处 《中国血液流变学杂志》 CAS 2014年第1期105-107,共3页 Chinese Journal of Hemorheology
关键词 甲状腺功能减退症 围生期 妊娠 左旋甲状腺素 妊娠结局 hypothyroidism perinatal period pregnancy L-thyroxine pregnancy outcome
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