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长链非编码RNA在肿瘤中的研究进展 被引量：8

New Research of Long Noncoding RNA in Tumor
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摘要 长链非编码RNA(Long noncoding RNAs,lncRNA)通常是指一类相对分子质量大于200 nt,且不能翻译为蛋白质的调控性RNA分子。lncRNA在机体生理及病理过程中均具有广泛的功能,尤其与恶性肿瘤发生发展关系密切。近年来lncRNA的研究进展迅速,本文就lncRNA在肿瘤中的最新研究进展作一综述。 Long noncoding RNAs(LncRNAs) are regulatory non-coding RNA molecules which are longer than 200 nucleotides. LncRNA has a wide range of functions under physiological and pathological conditions, and especially closely associated with the development of malignant tumor. LncRNA research has got significant advances in recent years. In this review, we summarize the recent research advances of LncRNA in cancer.
作者 张彬彬 殷媛 黄朝晖
机构地区 江南大学附属医院 无锡市肿瘤研究所
出处 《肿瘤防治研究》 CAS CSCD 北大核心 2014年第6期669-673,共5页 Cancer Research on Prevention and Treatment
基金 国家自然科学基金资助项目(81000867 81272299) 江苏省医学重点人才 江苏"333"工程 江苏省政府留学奖学金资助
关键词 长链非编码RNA 肿瘤 基因调控 LncRNA Tumor Gene regulation
分类号 R73 [医药卫生—肿瘤]
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参考文献11

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共引文献62

同被引文献35

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引证文献8

二级引证文献20

肿瘤防治研究
2014年 第6期

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