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^(89)Sr联合内分泌疗法治疗前列腺癌骨转移的疗效观察 被引量：2

Therapeutic efects of Strontium-89 combined with endocrine therapy for treatment of bone metastasis in patients with prostate cancer
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摘要 目的探讨89锶(89Sr)联合内分泌疗法治疗前列腺癌骨转移性疼痛的疗效。方法将64例确诊为前列腺癌且具有骨转移病灶并伴有疼痛的患者随机分为两组:89Sr联合内分泌治疗组42例,单纯采用内分泌治疗组26例,观察治疗后两组的止痛疗效、骨转移灶变化、血常规及生化指标的变化。结果治疗前两组患者的疼痛级数间差异无显著性意义(P>0.05)。治疗后联合治疗组患者疼痛级数较单纯内分泌组显著降低(P<0.05);联合治疗组患者骨转移病灶治疗有效率较单纯内分泌组显著升高(P<0.05)。结论 89Sr联合内分泌疗法能迅速有效地缓解前列腺癌骨转移疼痛,使骨转移病灶缩小或消失,副作用小,其疗效明显优于单纯内分泌疗法。 目的探讨89锶(89Sr)联合内分泌疗法治疗前列腺癌骨转移性疼痛的疗效。方法将64例确诊为前列腺癌且具有骨转移病灶并伴有疼痛的患者随机分为两组:89Sr联合内分泌治疗组42例,单纯采用内分泌治疗组26例,观察治疗后两组的止痛疗效、骨转移灶变化、血常规及生化指标的变化。结果治疗前两组患者的疼痛级数间差异无显著性意义(P&gt;0.05)。治疗后联合治疗组患者疼痛级数较单纯内分泌组显著降低(P&lt;0.05);联合治疗组患者骨转移病灶治疗有效率较单纯内分泌组显著升高(P&lt;0.05)。结论 89Sr联合内分泌疗法能迅速有效地缓解前列腺癌骨转移疼痛,使骨转移病灶缩小或消失,副作用小,其疗效明显优于单纯内分泌疗法。
作者 黄越
机构地区 丹东市中心医院骨科
出处 《中国医学工程》 2011年第3期3-5,共3页 China Medical Engineering
关键词 前列腺肿瘤 锶放射性同位素 放射疗法 内分泌疗法 prostatie neoplasms strontium radioisotopes radiotherapy endocrinotherapy
分类号 R [医药卫生]
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参考文献6

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二级参考文献34

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中国医学工程
2011年 第3期

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