摘要
目的探讨血浆抗凝血活酶Ⅲ活性在急性脑梗死患者中的变化及其临床意义。方法选择急性脑梗死者51例,对照组30例,采用发色底物方法、凝固法、凝血酶比浊法分别进行检测,分析血浆抗凝血酶Ⅲ活性(AT-Ⅲ)、血浆凝血酶原时间(PT)、活化部分凝血酶原时间(APTT)、血浆纤维蛋白(Fg)含量;另外选择30例本院门诊健康体检者作为对照组。结果脑梗死患者血浆AT-Ⅲ活性为(87.2±12.9)%,对照组为(95.9±12.8)%,两者比较差异有统计学意义(P<0.05),而PT、APTT、Fg含量比较差异无统计学意义(P>0.05)。结论AT-Ⅲ可作为一种诊断脑梗死的较敏感指标。
Objective To detect the level of serum AT-Ⅲ,PT,APTT and Fg in patients with cerebrovascular disease and discuss the change and clinical significance.Methods All samples were divided into two groups of ischemic stroke group(51 cases) and control group(30 cases).AT-Ⅲ,PT,APTT and Fg were detected by using chromogenic substrate methods,clot methods and clauss methods.Results The AT-Ⅲ level in ischemic stroke group was(87.2±12.9)% and that of control group was(95.9±12.8)%,the AT-Ⅲ level was significant lower in ischemic stroke group than that in control group;PT,APTT and Fg content had no significant difference between ischemic stroke group and control group.Conclusion The serum AT-Ⅲ can be sensitive index for diagnosing ischemic stroke.
出处
《中国卫生工程学》
CAS
2009年第S1期1-3,共3页
Chinese Journal of Public Health Engineering
