摘要
目的：探讨血清胃泌素在维、汉两族中的差异及其病理生理学意义。方法：通过放射免疫法测定维汉两族胃溃疡（ＧＵ）、十二指肠溃疡（ＤＵ）、胃癌（ＧＣ）患者血清胃泌素水平。结果：①两族正常组及慢性浅表性胃炎（ＣＳＧ）组间血清胃泌素水平无显著性差异；两族ＧＵ、ＤＵ、ＧＣ患者均存在一定的高胃泌素血症，与本族正常组及ＣＳＧ组比较均有显著性差异（Ｐ均＜０．０１）；②两族胃底贲门癌及胃窦癌血清胃泌素水平显著高于本族ＧＵ及ＤＵ患者；③维族胃底贲门癌及胃窦癌血清胃泌素水平均显著高于汉族（Ｐ均＜０．０５）。结论：消化性溃疡（ＰＵ）及胃癌患者血清胃泌素水平似有助于胃良。
Purpose:To analyze the difference and its patho-physiologic significance of the plasma gastrin contents in patients with peptic ulcer(PU)and gastric cancer(GC)between the Uygur and Han nationalities. Methods:Using the radio-immunizing method to determine the plasma gastrin levels in patients with gastric ulcer(GU),duodenal ulcer(DU)and GC between two nationalities.Results:There was no significant difference of plasma gastrin levels between two nationalities in control groups and chronic superficial gastritis(CSG)groups.The gastrin levels in patients with GU,DU,GC increased in both nationality groups and showed significant difference to their respective control groups and CSG groups(all P<0.01).The plasma gastrin levels in patients with fundal cardial GC and antrum GC were all higher than their own control groups in both nationalities,in which,the Uygur patients showed even more higher gastrin level than that of Han patients(P<0.05).Conclusion:It is valuable to determine the plasma gastrin level in patients with GU,DU and GC for distinguishing the benignity and malignancy.
出处
《西北国防医学杂志》
CAS
1998年第3期23-24,共2页
Medical Journal of National Defending Forces in Northwest China
