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肾素-血管紧张素系统在血管迷走性晕厥中的作用 被引量:1

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摘要 本研究采用直立倾斜80°的方法,观察了14例(21~52岁)有反复晕厥史的血管迷走性晕厥患者及10例(25~51岁)无晕厥史的健康对照者。分别在平卧位、倾斜位即刻、2、5、10、15、20、25min或晕厥发作时采静脉血测血浆肾素活性(PRA)、血浆血管紧张素Ⅱ(AT-Ⅱ)及醛固酮(ALD)的浓度。结果显示,患者在发生晕厥时(n=9),血压显著下降,PRA、AT-Ⅱ、ALD浓度迅速增加,显著高于未发生晕厥的患者(n=5)及正常对照(n=10)。研究表明,循环肾素(R)、AT-Ⅱ、ALD都迅速参与体循环的调节作用,但它们的增高不是引起晕厥的直接原因。
出处 《医学研究生学报》 CAS 1996年第2期10-13,共4页 Journal of Medical Postgraduates
基金 南京总医院科研基金
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