摘要
The retinoblastoma (Rb) gene probe p123 M 1.8 andP68 Rs2.0 were used to study the frequencies of the.BamHI and Rsal restriction fragment length polymorphisms (RFLPs) in the Rb gene among the population of Han nationality in Guangdong Province.The result showed that the heterozygotic rate of the Rsal locus was only 55.0%. Linkage study of the BamHI and the Rsal RFLPs demonstrated that 10.s% of the Rsal polymorphic loci were heterozygous for the BamHI RFLP.Thus the combined use of the two RFLPs can give information for about 65.5% of the population.
The retinoblastoma (Rb) gene probe p123 M 1.8 andP68 Rs2.0 were used to study the frequencies of the.BamHI and Rsal restriction fragment length polymorphisms (RFLPs) in the Rb gene among the population of Han nationality in Guangdong Province.The result showed that the heterozygotic rate of the Rsal locus was only 55.0%. Linkage study of the BamHI and the Rsal RFLPs demonstrated that 10.s% of the Rsal polymorphic loci were heterozygous for the BamHI RFLP.Thus the combined use of the two RFLPs can give information for about 65.5% of the population.
