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IMMUNOHISTOCHEMICAL STUDY OF ESTROGEN AND PROGESTERONE RECEPTOR IN THYROID TISSUES OF AUTOIMMUNE THYROID DISEASE 被引量:1

IMMUNOHISTOCHEMICAL STUDY OF ESTROGEN AND PROGESTERONE RECEPTOR IN THYROID TISSUES OF AUTOIMMUNE THYROID DISEASE
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摘要 ShiBingyin(施秉银);ZhangXuchin(张学斌);GaoHui(高慧);MaXiuping(马秀萍);WangMin(王敏)IMMUNOHISTOCHEMICALSTUDYOFESTROGENANDPROGESTERONERECEPT... Estrogen receptor(ER) and progesterone receptor (PgR) in core-needle biopsied thyroidtissues of 30 cases of autoimmune thyroid disease and 2 cases of simple gotter were measured usingenzyme-linked histochemical technique. The results showed that the frequences of presence of ER inGraves' disease (GD) and Hashimoto's thyroditis(HT) were 50% (9/18) and 58. 3K (7/12) respectively ; and those of PgR were 11. 1 % (2/18) in GD, 16. 2% (2/7) in HT. Both ER and PgR werenegative in simple gotter. This study demonstrated that the content of ER in thyroid tissues of autoimmune thyroid disease was relatively high, suggesting that estrogen may play a role in the development of the disease.
出处 《Journal of Pharmaceutical Analysis》 CAS 1994年第2期112-113,133,共3页 药物分析学报(英文版)
关键词 ESTROGEN RECEPTOR PROGESTERONE RECEPTOR immunuohistochemistry AUTOIMMUNE THYROID DISEASE estrogen receptor progesterone receptor immunuohistochemistry autoimmune thyroid disease
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