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苏子降气汤的药理研究 I.主要药效学 被引量:5

Pharmacological Studies of Su Zi Jiang Qi Decoction (SZJQD) Ⅰ. On the Main Phanmacodynamics
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摘要 苏子降气汤对小鼠氨水性咳嗽、豚鼠实验性哮喘、巴豆油引起的小鼠耳部炎症以及实验性I型变态反应均有显著的抑制作用;对正常及由组胺、乙酰胆碱所致痉挛状态的离体气管均有显著的松弛作用,且不被心得安所拮抗;能明显减轻SO_2慢性支气管炎模型的病理改变;对呼吸道酚红排泌的影响不明显。 This paper has reported the pharmacological effects of SZIQD ou the main pharma-cdynamics. The results were as follow: ( 1 ) Ammonia-induced cough of mice, histamine-acetyl choline chloride-induced asthma of guinea pigs, oil of Croton seed-induced inflammation of mice, and experimental allergy of type f1 of rats were markedly inhibited by SZJQD. ( 2 ) The normal respiratory tract segments and histamine-acetyl choline-induced convulsing respiratory tract segments were markedly relaxed by SZJQD, which couldn't be prevented by propranolol, the bata receptor blocker. (3) Index of sulfur dioxide-induced chronic bronchitis models were significantly decreased by SZJQD.
机构地区 成都中医学院
出处 《中药药理与临床》 CAS CSCD 1992年第5期13-15,共0页 Pharmacology and Clinics of Chinese Materia Medica
关键词 苏子降气汤 镇咳 平喘 抗炎 抗过敏 Su Zi Jiang Qi Decortion cough asthma inflsmmattioa model of chronic bronchitis.
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