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168例新生儿先天性心脏病的临床与病理

CLINCAL AND PATHOLOGICAL INVESTIGATION OF 168 NEWBORNS WITH CONGENITAL HEART DISEASE
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摘要 本文报道经尸检证实的新生儿先天性心脏病168例。同期本院新生儿尸检1170例,先心病占尸检总数14%,为新生儿畸形的首位。先心病发病率最高是室间隔缺损(VSD)22%,其次是房间隔缺损(ASD)18%。全部ASD病人和84%VSD病人死于心脏外原因,以感染与围产期疾患为主。而左心发育不良综合症(100%)、大动脉转位(80%)、肺动脉闭锁伴室间隔完整(78%)、单心室(57%)、永存动脉干(55%主要死于严重的心脏畸形。 This paper reports 168 cases of live-birth newborns with autopsies proved neonatal congenital heart disease(CHD) 1956-1989. Of the neonatal autopsies 1170, CHD accounted for 14%, the highest frequency of newborn malformation among neonatal autopsies. The highest frequency of CHD was VSD(20%), then ASD(18%). Most of the cases of VSD(94%) and all the cases of ASD died of extracardial causes mainly with infections and perinatal diseases, meanwhile hypoplastic left heart syndrome(100%), complete transposition of great artery(80%), pulmonary atresia with nor- mal septum (78%), single ventricle (57%), persistent truncus arteriosus (55%), mainly died of severe heart malformations. The authors come to conclusion for the aristogenesis that attention should be payed to the imp- rovemnnt of pregnancy care and the enhancement of prevention level of perinatal diseases; neonatal CHD should be early diagnosed and treated in time, so as to reduce signicantly the mortality in neonates with CHD.
出处 《中国新生儿科杂志》 CAS 1992年第3期97-99,141,共4页 Chinese Journal of Neonatology
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