摘要
目的：评估复方苦参注射液治疗恶性肿瘤癌性疼痛的临床效果。方法选取2010年2月～2013年4月间湖北省黄冈市中心医院进行治疗的恶性肿瘤患者100例为研究对象进行回顾性分析；根据随机数字表随机均分为对照组（n=50）和研究组（n=50）。在接受常规治疗的基础上，对照组加用三阶梯止痛法，研究组加用复方苦参注射液；采用疼痛数学评估法（numerical rating scale，NRS）评估2组患者治疗前后的疼痛状况并进行对比；同时用Karnofsky评分法评估2组患者治疗前后的生活质量评分并进行对比。结果研究组治疗疼痛的效果好于对照组，差异具有统计学意义（P＜0.05）；研究组生活质量评分优于对照组的，差异具有统计学意义（P＜0.05）。结论复方苦参注射液治疗恶性肿瘤癌性疼痛的临床疗效较好，且能够显著改善患者生活质量。
Objective To evaluate the clinical efifcacy of Matrine injection on malignant cancer pain treatment. Methods 100 patients in Central Hospital of Huanggang from February 2010 to April 2013 were randomly divided into two groups(control group and research group) for retrospective study(n=50). Based on the conventional treatment, control group were received three-step analgesic ladder, and research group were treated with matrine injections. The pain scores and Karn of sky scores were evaluated and compared before and after treatment in each group, and were compared between two groups. Results The pain score and Karn of sky score in research group after treatment were signiifcantly better than control group(P<0.05). Conclusion Matrine injection could relief pain level and improve patients'' quality of life of malignant cancer patient.
出处
《中国生化药物杂志》
CAS
北大核心
2014年第2期104-105,共2页
Chinese Journal of Biochemical Pharmaceutics
基金
江苏省国际合作项目(BZ2011034)
