摘要
间充质干细胞(MSCs),是一种具有自我更新能力和多向分化潜能的成体干细胞,是组织工程中的"种子细胞"。MSCs的研究,包括最初的分化潜能和近几年热门的旁分泌功能,都有了相当的进展,而且在多个领域也开展了临床上的应用。在男性不育领域内,MSCs研究目前仍在动物实验阶段中摸索,但随着人们对MSCs潜能的认识加深,基于MSCs的治疗将会是一种新颖而有效的方法。
Mesenchymal stem cells( MSCs) are somatic stem cells capable of self-renewing and multipotent differentiation. They are also referred to as ' seed cells' in tissue engineering. Recent years have witnessed great advances in the studies of the differentiative potential and paracrine function of MSCs,as well as in their clinical applications in several fields. As for their application in male infertility,researches are still in the stage of animal experiments. However,with deeper insights into their huge potential, novel and effective MSC-based therapies for male infertility will come into being in the near future.
出处
《中华男科学杂志》
CAS
CSCD
2013年第10期949-952,共4页
National Journal of Andrology
基金
湖北省科技厅研究与开发项目(2008BCC007)~~
关键词
间充质干细胞
分化潜能
旁分泌功能
男性不育症
mesenchymal stem cell
differentiative potential
paracrine function
male infertility
