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阻塞性睡眠呼吸暂停低通气综合征与胰岛素抵抗

Obstructive sleep apnea-hypopnea syndrome and insulin resistance
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摘要 阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea hypopnea syndrome,OSAHS)是具有潜在危害性的疾病,可引起一系列并发症,严重时甚至可导致死亡.其主要表现为睡眠时打鼾并伴有呼吸暂停和(或)低通气,夜间反复发生低氧和高碳酸血症以及睡眠结构紊乱,并进而导致白天嗜睡、记忆力下降,可出现自主神经功能紊乱乃至心脑血管并发症、多脏器损害等,严重影响患者的生活质量和寿命.进一步的研究结果揭示,OSAHS本身作为多种全身疾患的独立危险因素参与诸如糖尿病、代谢综合征、冠心病、卒中等的发生发展,而OSAHS所致的胰岛素抵抗在这些并发症的发生过程中起着至关重要的作用.
出处 《中华糖尿病杂志》 CAS 2010年第2期-,共3页 CHINESE JOURNAL OF DIABETES MELLITUS
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