摘要
非动脉炎性前部缺血性视神经病变(NA-AION)是一种中老年人常见的急性致盲性眼病,常会引起视网膜神经纤维层缺损和黄斑厚度及容量变化。急性发生的暂时无灌注或低灌注状态导致视神经乳头急性缺血是引起NA-AION的主要原因。高血压、夜间低血压、高脂血症、糖尿病、动脉粥样硬化等全身系统疾病,无视杯或小视杯及显著的眼内压升高等眼局部疾病均是本病发生的危险因素。NA-AION的临床表现为中心视力不同程序下降及周边视野缺损等改变。在NA-AION的诊断过程中,眼底和视野检查、荧光素眼底血管造影、视觉诱发电位是常用的检查方法。近年来,光学相干断层扫描也逐步应用于NA-AION的诊断。笔者仅对NA-AION的病因和临床表现进行分析,并就辅助检查对本病的临床诊断意义进行述评。
Nonarteritic anterior ischemic optic neuropathy ( NA-AION ) is a common causing blindness disease among the elderly, and usually causes retinal nerve fiber layer ( RNFL) defection as well as macular thickness and volume changes.Acute temporary non-perfusion or hypoperfusion which caused acute optic nerve ischemic is the main reason of NA-AION. Hypertension, nocturnal hypotension, hyperlipidemia, diabetes, atherosclerosis and other systemic diseases, no/little optic cup and significant higg intraocular pressure and other ocular local diseases are also risk factors.The clinical manifestations of NA-AION are different procedures decreased of central vision and peripheral visual field defects and so on. The diagnostic methods of NA-AION include fundus examination, visual field, fundus fluorescein angiography (FFA), visual evoked potential (VEP).In recent years, optical coherence tomography (OCT) is gradually applied to the diagnosis of NA-AION.In this paper, the author analyzed the etiology and clinical manifestations of NA-AION, and surveyed the application of assistant examinations in clinical diagnosis of this disease.
出处
《中华眼科医学杂志（电子版）》
2013年第1期5-9,共5页
Chinese Journal of Ophthalmologic Medicine(Electronic Edition)
关键词
非动脉炎性前部缺血性视神经病变
病因
诊断
光学相干断层扫描
Non-arteritic anterior ischemic optic neuropathy
Optical coherence tomography
Retinal nerve fiber layer
Macular thicknes and volume
