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^(31)P磁共振波谱评价心肌能量代谢和功能的临床应用研究进展 被引量：2

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摘要 心脏磁共振波谱(magnetic resonance spectroscopy,MRS)是目前唯一能够用于研究心肌代谢功能的非侵入性检测方法,没有放射性且不用引入任何对比剂或同位素示踪剂[1-3],这使得各种原子核的MRS在心肌代谢方面的应用前景格外吸引人。目前在心脏方面有应用的包括31P-MRS、
作者 朱熠 成官迅
机构地区 南方医科大学南方医院影像中心
出处 《功能与分子医学影像学（电子版）》 2012年第3期224-227,共4页 Functional and Molecular Medical Imaging(Electronic Edition)
关键词 心脏 磁共振波谱分析 代谢
分类号 R445.2 [医药卫生—影像医学与核医学]
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参考文献21

  • 1韩路军,张雪林.心肌^1H-MRS的临床应用[J].临床放射学杂志,2010,29(1):133-135. 被引量：1
  • 2常时新,孔祥泉.心脏^(31)P-MRS的现状及临床应用前景[J].临床放射学杂志,2005,24(11):1023-1025. 被引量：2
  • 3Beer M,Seyfarth T,Sandstede J,et al.Absolute concentrations of high-energy phosphate metabolites in normal, hypertrophied, and failing human myocardium measured noninvasively with (31)P-SLOOP magnetic resonance spectroscopy. Journal of the American College of Cardiology . 2002
  • 4Phan TT,Abozguia K,Nallur Shivu G,et al.Heart fail-ure with preserved ejection fraction is characterized by dy-namic impairment of active relaxation and contraction of the left ventricle on exercise and associated with myocar-dial energy deficiency. Journal of the American College of Cardiology . 2009
  • 5Rijzewijk LJ,van der Meer RW,Lamb HJ,et al.Altered myocardial sub-strate metabolism and decreased diastolic function in nonischemic human diabetic cardiomyopathy:studies with cardiac positron emission tomo-graphy and magnetic resonance imaging (J). Journal of the American College of Cardiology . 2009
  • 6Raman SV.The hypertensive heart.An integrated understanding in-formed by imaging. Journal of the American College of Cardiology . 2010
  • 7Holloway CJ,Suttie J,Dass S,Neubauer S. et al.Clinical cardiac magneticresonance spectroscopy. Progress in Cardiovascular Diseases . 2011
  • 8Kolwicz S C, Jr,Tian R.Assessment of cardiac function and energetics in isolated mouse hearts using 31P NMR spectroscopy. Journal of visualized experiments . 2010
  • 9Schocke,MFH,Metzler,B,Wolf,C.Impact of aging on cardiac high-energy phosphate metabolism determined by phosphorus-31 2-dimensional chemical shift imaging (31P 2D CSI). Magnetic Resonance Imaging . 2003
  • 10Hu Q,Wang X,Lee J,et al.Profound bioenergetic abnormalities inperi-infarct myocardial regions. American Journal of Physiology Heart and Circulatory Physiology . 2006

二级参考文献45

  • 1lngwall JS,Weiss RG. Is the failing heart enerD' strayed? On using chemical energy to support cardic function. Circ Res,200d. ,95:135.
  • 2Stanley WC, Recchia FA, Lopaschuk GD. Myocardial substrate metabolism in the normal and failing heart. Physiol Rev ,2005,85 : 1093.
  • 3Brittl JA, DeLayre J, Ingwall JS. Rate equation for creatine kinase predicts the in vivo reaction velocity:31P-NMR surface coil studies in brain,heart, and skeEetal muscle of the living rat. Biochemistry, 1987,26:6083.
  • 4Brittl JA, Ingwall JS. Reaction rates of ereatine kinase and ATP synthesis in the isolated rat heart. J Biol Chem, 1985,260:3512.
  • 5Bottomley PA,Weiss RG. Non-invasive magnetie-resonance detection of creatine depletion in non-viable infarcted myoeardium. The Lancet, 1998,351:714.
  • 6Nakae I, Mitsunami K,Matsuo S,et al. Myocardial Crealine Concentration in Various Nonischemic Heart Diseases Assessed by 111 Magnetic Resonance Spectroscopy. Circ J,2005,69 : 711.
  • 7Nakae I, Mitsunami K, Matsue S,et al. Creatine depletion and altered fatty acid metabolism in diseased human hearts:clinical investigation using 1 H Magnetic resonance spectroscopy and 123I BMIPP myocardial scintigraphy. Acta Radiologica,2007 ,48 :436.
  • 8Unger RH. Minireview : weapons of lean body mass destruction : the role of ectopic lipids in the metabolic syndrome. Endocrinology., 2002,144:59.
  • 9Szezepaniak LS, Dobbins RL,Stein DT,et al. Bulk magnetic susceptibility effects on the assessment of intra and extramyocellular lipids in vivo. Magn Reson Med,2002,47:607.
  • 10Browning JD, Szezepaniak LS, Dobbins R, et al. Prevalence of hepatic steatosis in an urban population in the united states:impact of ethnicity. Hepatology ,2004,40 : 1387.

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功能与分子医学影像学（电子版）
2012年 第3期

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