摘要
目的:探讨联合应用左氧氟沙星和头孢哌酮舒巴坦治疗老年肺炎的临床疗效。方法:采用随机数字表法将我院2010年3月～2012年3月收治的200例老年肺炎患者平均分为两组,即对照组和联合治疗组。对照组患者应用头孢哌酮舒巴坦进行治疗,联合治疗组患者联合应用左氧氟沙星和头孢哌酮舒巴坦进行治疗。治疗结束后,比较两组患者的治疗总有效率、病原菌转阴率和不良反应发生率。结果:对照组患者的治疗总有效率为76.0%,联合治疗组患者的治疗总有效率为95.0%,联合治疗组患者的治疗总有效率高于对照组患者的治疗总有效率,且两者间的差异具有统计学意义(p<0.05);联合治疗组患者的病原菌转阴率为93.0%,对照组患者的病原菌转阴率为78.0%,联合治疗组患者的病原菌转阴率高于对照组的病原菌转阴率,且两者间的差异具有统计学意义(p<0.05);两组患者不良反应发生率的差异无统计学意义(p>0.05)。结论:联合应用左氧氟沙星和头孢哌酮舒巴坦治疗老年肺炎能够有效改善患者的临床症状、提高患者的病菌清除速率,是一种值得在临床上推广和应用的老年肺炎治疗法。
Objective To investigate the therapeutic effect of levofloxacin combined with cefoperazone sulbactam on elderly pneumonia. Methods 200 patients with elderly pneumonia were chose in the period from March 2010 to March 2012 in our hospital and randomly divided into two groups including control group (100 patients) with cefoperazone sulbactam?treatment and combined treatment group(100 patients)with levofloxacin treatment on the basis of control group treatment;and the clinical total treatment efficiency,pathogen seroconversion rate and complication incidence of both groups were compared.Results The clinical treatment efficiency of control group and combined treatment group were separately 76.0%,95.0%;The clinical total treatment efficiency of combined treatment group were significantly better than control group (p<0.05).The pathogen seroconversion rate of combined treatment group were significantly better than control group(p<0.05).And there was no significant difference in complication incidence between control group and combined treatment group(p>0.05).Conclusion Levofloxacin combined with cefoperazone sulbactam on elderly pneumonia can efficiently improve clinical symptoms and pathogen seroconversion effects, have no serious adverse effects,and is worthy of clinical application.
出处
《求医问药（下半月）》
2013年第1期422-423,共2页
Seek Medical and Ask The Medicine
关键词
左氧氟沙星
头孢哌酮舒巴坦
老年
肺炎
疗效
levofloxacin
cefoperazone sulbactam
elderly
pneumonia
therapeutic effects
