摘要
目的 评价弹性应变率比值(SR)在超声引导下甲状腺细针穿刺(US-FNA)中的应用价值.方法 对216例患者共222例甲状腺结节的临床资料、二维超声图像和SR进行logistic回归分析,评价各变量尤其是SR的诊断效能,统计SR法、US-FNA法和联合法诊断甲状腺结节良恶性的灵敏度、特异度和准确率.结果 多因素分析筛选出3个具有统计学意义的特征变量,按OR值高低依次为:SR、结节回声、年龄.SR法、US-FNA法和联合法诊断甲状腺结节良恶性的灵敏度、特异度和准确率分别为85.4％、82.1％、83.3％;91.5％、82.1％、85.6％;97.6％、94.3％、95.5％.结论 SR＜0.5是诊断甲状腺恶性结节最重要的危险因素,SR联合US-FNA法后显著提高了US-FNA诊断的灵敏度、特异度和准确率,在US-FNA中具有重要的临床意义.
Objective To evaluate the value of elastic strain ratio (SR) in ultrasound guided fine needle aspiration (US-FNA) of thyroid nodule.Methods A total of 222 thyroid nodules from 216 patients were reviewed and analyzed by Logistic regression of clinical data,2D ultrasound,and SR.The odds ratios of variables in the equation were compared to assess various variables,especially of SR in the diagnosis.The sensitivity,specificity,and accuracy of the SR method,US-FNA method,and combined method were calculated.Results Three statistically significant features finally entered the Logistic regression model,followed by SR,echo,and age according to the odds ratio.The sensitivity,specificity,and accuracy of the SR method,US-FNA method and combined method were 85.4％,82.1％,83.3％ ; 91.5％,82.1％,85.6％ ; 97.6％,94.3％,95.5％ respectively.Conclusions SR＜0.5 is the most important risk factor in differential diagnosis of thyroid malignant nodules from benign nodules.SR raises the sensitivity,specificity,and accuracy of US-FNA method and plays an important role in diagnosing thyroid nodules via US-FNA.
出处
《中华内分泌代谢杂志》
CAS
CSCD
北大核心
2014年第4期-,共5页
Chinese Journal of Endocrinology and Metabolism
