摘要
本文报道了宁夏盐池县马儿庄,改水8年防治地方性氟中毒,在水氟、氟斑牙、氟骨症患者症状与体征、尿氟、以及骨X线片骨密度、骨结构等方面的变化。水氟多次检测稳定在0.8mg/L。成人氟斑牙改水前后病损改变不大,而改水后出生的儿童,却基本不患氟斑牙或病损程度极轻。氟骨症患者的症状与体征明显减轻占52.8％。精选26例X线拍片动态随诊对比观察,骨密度、骨结构明显减轻占76.92％。连续8年尿氟检测,由改水前15.61mg/L,分别降至5.80、5.01、3.71、3.07mg/L,第一年下降幅度最大。除第6与第8年两个样本均值无显著性外(P>0.05),其他各年都有极显著性(P<0.01)。但该病区均值仍高于宁夏非病区正常上限2.60mg/L水平。
Effectiveness of controlling endemic fluorosis through de-fluoridation by improvement of drinking water quality for 8 years, whose assessment was based on the changesin fluoride levels in water source, symptoms and signs of the cases of dental and skeletal fluorosis, their urinary fluoride levels and bone density and structures showed on their roentgenograms, was observed in Marzhuang village in Yanchi county, the Ningsia Hui Autonomous Region, China. Fluoride was found in water source at the concentration of 0.8mg /l throughdeterminations of water samples. It was observed that among the adult cases, condition of dental fluorosis did not vary, singnificantly, before and after improving water quality. Among the children, however, who were born after improvement of water quality, only a few cases of dental fluorosis were found, with a mild condition of mottled teeth. Obvious improvement of symptoms and signs occurred in 52.8% of cases of skeletal fluoriosis. Adynamic contrast follow-up survey made by roentgenography among 26 selected cases of skeletal fluorosis revealed that the density and structures of their bones were obviously improved in 76.92% of those cases.
The continuous 8 year's determinations of fluoride concentrations in urinary samples from the cases have revealed that the concentrations of their urinary fluoride have reduced from 15.61mg/l before improvement of water quality to 5.80mg/l, 5.01mg/l, 3.71mg/l after that ,respectively, with the first year's reduction of greatest range. As shown in Table 1, the mean values of fluoride determinations from all of urinary samples obtained in other different years are statisically significant (p>0.01),,except for the two samples obtained the 6 th-and-8 th years, respectively,whose mean values of fluoride determinations are not significant (P>0.05), statistically. However, the mean values of fluoride concentrations from urinary samples obtained in the endemic area are higher than the normal upper limit value of 2.60 mg /l obtained from the non-endemic areas in Ningsia.
出处
《地方病通报》
1993年第3期49-52,共4页
Endemic Diseases Bulletin
关键词
地方性
氟中毒
氟骨症
氟斑牙
改水
Endemic fluorosis
Skeletal fluorosis
Dental fluorosis
