摘要
目的 :探讨慢性阻塞性肺病 (COPD)患者血清神经肽Y(NPY)水平的变化及其临床意义。方法 :采用放射免疫分析测定 4 0例COPD患者和 30例非COPD患者的血清NPY水平进行统计分析。结果 :COPD组血清NPY水平显著高于对照组 (130 36± 2 0 5 8) pg/mlvs (86 6 2± 13 0 2 ) pg/ml(t =10 .2 0 1,P <0 0 1)。Ⅰ、Ⅱ、Ⅲ期COPD患者间神经肽Y水平有显著差异 (F =2 0 .334,P <0 0 1)。结论 :COPD患者血清NPY显著升高 ,且与分期相关。
Objective To Study the clinical significance of serum neruopeptide Y level changes in patients with chronic obstructive pulmonary diseases (COPD). Methods The serum neuropeptide Y levels were determined by radioimmunoassay in 40 patients with chronic obstructive pulmonary diseases (COPD) and 30 patients without COPD. Results Mean serum neuropeptide Y level in patients with COPD was significantly higher than that in ptients without COPD (130.36±20.58pg/ml vs 86.62±13.02pg/ml; t=10.201, p<0.01). Moreover , the levels in patients of the different stages (Ⅰ、Ⅱ、Ⅲ) of COPD were significantly different from one another (F=20.334, p<0.01). Conclusion The serum neuropeptide Y levels increased significantly in patients with COPD and were correlated to the diferent disease stages.
出处
《放射免疫学杂志》
CAS
2004年第3期175-176,共2页
Journal of Radioimmanology
