摘要
目的 研究新型纳米复合材料 n HA- PA6 6用作根管充填材料的组织反应。方法 采用 n HA- PA6 6对犬牙实验性根尖周炎进行根管充填 ,通过组织学方法对犬牙根尖周组织的反应进行评价。结果 n HA- PA6 6根管充填一月后 X片表现为根尖周骨质吸收区域缩小 ,组织切片上犬牙根尖周组织主要表现为轻到中度炎症反应 ;三月后 X片上骨质吸收面积进一步减小 ,镜下则见有较好的修复反应发生 ;其炎症反应较小而修复反应发生较早。结论 n HA- PA6
Objective To assess the dogs' tissue reaction to nHA PA66 which is prepared to be used as a new root canal filling sealer. Methods The experimental apical periodontitis of dogs was induced first, then nHA PA66 was used in the test groups while CCQ was used in the control group. The reactions of periapical tissues were measured by histological means. Results One month after nHA PA66 was used in root canal filling, the dogs' periapical tissues showed mild to moderate inflammatory reactions, the X ray films showed decreased radiolucent area as compared with the previous film. Three months later, tissue repairs occurred, which exhibited even more decreased radiolucent area on X ray films. nHA PA66 caused weak inflammatory reaction while the reparative reaction happened early. Conclusion nHA PA66 has good tissue compatibility and is a potential sealer for root filling in clinical use.
出处
《四川大学学报（医学版）》
CAS
CSCD
北大核心
2004年第4期522-524,共3页
Journal of Sichuan University(Medical Sciences)
基金
四川省科委科技攻关项目 ( 0 2 SG0 2 2 -0 0 1)资助
