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急性起病的非甲非乙型病毒性肝炎的病原分析

Acute onset of Non-A, Non-B viral hepatitis:An etlological analysis
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摘要 对HBsAg(一)、IgM抗HAV(一)临床诊断为急性非甲非乙肝炎63例,进行了病原学鉴定。以聚合酶链反应(PCR)检测HBV DNA,HCV RNA,并检测了IgM抗HBc和抗HCV血清抗体。诊断为急性丙型肝炎15例(23.8%),急性乙型肝炎20例(31.7%),慢性HBV携带者急性活动19例(30.2%),乙、丙型混合肝炎2例(3.2%),病原不明7例(11.1%)。结果表明在临床所谓的急性非甲非乙肝炎中,急性和慢性乙型肝炎仍占多数。 Further etilogical identification was carried out on 63 cases with negative hepatitis B surface antigen and IgM antibody against hepatitis A virus; they were diagnosed as acute hepatitis non-A non-B clinically.Viruses were dete-cted by polymerase chain reaction, serum IgM antibody to hepatitis B core by the Abbott kit, and antibody to hepatitis C virus by an EIA using synthesized oligopeptide CP-36.The results revealed that 15 cases ( 23.8% ) were acute hepatitis C, 20 ( 31.7% ) acute hepatitis B, 19 ( 30.2% ) acute episode of chronic asymptomatic hepatitis B virus carriers, two mixed hepatitis B and C, and seven remained aetiologically unknown.Among the so-called acute hepatitis non-A, non-B clinically the majority of cases were still acute and chronic hepatitis B.
出处 《第一军医大学学报》 CSCD 1993年第1期12-15,共4页 Journal of First Military Medical University
关键词 丙型肝炎 病原学 viral hepatitis acute non-A non-B hepatitis hepatitis B hepa-titis C
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参考文献5

  • 1杨守昌,第一军医大学学报,1992年,12卷,14页
  • 2骆抗生,J Med Virel,1991年,35卷,55页
  • 3周荣,第一军医大学学报,1991年,11卷,181页
  • 4骆抗生,中华内科杂志,1991年,30卷,21页
  • 5骆抗生,中华内科杂志

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