摘要
目的 总结急性呼吸窘迫综合征 (ARDS)的诊断治疗经验。方法 收集 1994年 1月至 2 0 0 3年 12月十年间急救科GICU收治的 16 5例ARDS患者临床资料 ,进行回顾性分析 ,其中男性患者 91例 ,女性 74例 ;年龄 11～ 90岁 ,平均年龄 5 7岁。将 1994年 1月至 1998年 12月 4 9例患者归入A组 ,1999年 1月2 0 0 3年 12月 116例患者归入B组。比较两组患者发病率、氧合指数、APACHEⅡ评分、带管时间、住院天数、发生与呼吸机相关性肺损伤 (VALI)、病死率。结果 A组患者发病率、氧合指数、APACHEⅡ评分、带管时间、住院天数、VALI、病死率分别为 1 5 %、 (16 3± 35 )、 (2 6 5± 3 3)分、 (2 8 6± 2 3)d、 (36 4±3 7)d、 12 2 %和 6 3 2 % ;B组分别为 4 7% ,除氧气指数和APACHEII评分两指标外 ,其余指标差异均有显著性。结论 随着对发病原因及发病机制的不断认识 ,综合救治方法的不断改进 ,ARDS患者临床救治时间明显缩短 ,病死率显著下降。
Abstract Objective To analyze our experience of 165 patients with acute respiratory distress syndrome(ARDS)?Methods 165 patients who had ARDS and admitted from July 1994 to December 2003 in GICU of emergency department were classified into two groups:group A included 49 patients from July 1994 to December 1998,and group B included 116 patients from July 1999 to 2003.Morbidity,PaO 2/FiO 2,acute physiology and chronic health evaluation Ⅱ(APACHE Ⅱ),days intubated,days in hospital,incidence of ventilator-associated lung injure(VALI)and mortality were compared.Results The morbidity,PaO 2/FiO 2,APACHEⅡ,days intubated,days in hospital,incidence of VALI and mortality of group A were 1.5%,(163±35),(26.5±3.3),(28.6±2.3)days,(36.4±3.7)days,12.2% and 63.2%,respectively;those of group B were 4.7%( P <0.05),(156±32)(P>0.05),(25.8±3.4)( P >0.05),(21.5±2.4)days ( P <0.05),(27.9±4.1)days( P <0.05),2.6%( P <0.05) and 30.1%( P <0.05) respectively.Conclusion Days of treatment of ARDS are shortened,and mortality decreases.
出处
《中华急诊医学杂志》
CAS
CSCD
2004年第6期403-405,共3页
Chinese Journal of Emergency Medicine
