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亚砷酸致急性肾功能衰竭 被引量:2

Acute renal failure in connection with arsenious acid
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摘要 Summary A 40-year-old man was admitted to hospital due to palpitation and fever for 1 month,and diagnosed as myelodysplastic syndrome, refractory anemia with excess blasts. Since it was failure to be treated with daunorubicin plus cytarabine for 2 courses, the patient was given an intravenous infusion of arsenious acid 10mg daily. Oliguria in the patient occurred at the 9th day of medication. Arsenious acid was discontinued. The patient’s manifestations were hypervolemia and systemic edema. Renal function test showed Cr 225.66μmol/L, BUN 1596.43mmol/L, serum potassium 5.05mmol/L. After limitation of water intake and administration of diuretic drugs,the symptoms with hypervolemia were lessened,the signs disappeared and renal function became normal. Summary A 40-year-old man was admitted to hospital due to palpitation and fever for 1 month,and diagnosed as myelodysplastic syndrome, refractory anemia with excess blasts. Since it was failure to be treated with daunorubicin plus cytarabine for 2 courses, the patient was given an intravenous infusion of arsenious acid 10mg daily. Oliguria in the patient occurred at the 9th day of medication. Arsenious acid was discontinued. The patient's manifestations were hypervolemia and systemic edema. Renal function test showed Cr 225.66μmol/L, BUN 1596.43mmol/L, serum potassium 5.05mmol/L. After limitation of water intake and administration of diuretic drugs,the symptoms with hypervolemia were lessened,the signs disappeared and renal function became normal.
出处 《药物不良反应杂志》 2004年第3期179-179,共1页 Adverse Drug Reactions Journal
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