摘要
目的:研究出生时间与脑卒中的发病频数、发病年龄、性别、脑卒中病变性质(缺血性、出血性)、脑卒中病灶侧别(左、右侧脑半球)以及与脑卒中死亡的关系。方法:832例首次发病的脑卒中患者为脑卒中组。832例无脑卒中病史和脑卒中征象,按1∶1比例与脑卒中组配对性别和出生年份相同而年龄相近者为对照组。采用太阳历和干支历记录研究对象的出生时间。采用圆形分布法等,统计分析各出生时间序列与卒中发病频数、发病年龄、性别、脑卒中病变性质、脑卒中病灶侧别以及与脑卒中死亡的关系。结果:在出生12个月份上脑卒中的频数分布有集中趋势(r=0.1195,P<0.001),脑卒中组832例中出生于冬季风季节(11月～第2年4月)者476例,对照组832例中出生于冬季风季节者417例,季节性分布两组比较差异有显著性意义(P<0.005)。脑卒中的发病年龄有以4个出生月份为周期的4月节律,4月周期中年龄均数高峰值与低谷值比较差异有显著性意义(P<0.001),高峰值、低谷值分别与对照组比较差异均有显著性意义(P<0.05)。在出生10日十天干周期上,男、女脑卒中的分布均有集中趋势(P<0.001),男、女间比较差异有显著性意义(P<0.005),男、女分别与对照组比较差异均有显著性意义(P<0.05)。在出生60甲子日周期上,缺血性。
AIM:To study the relationships of birth date of stroke patients with the stroke frequency,age of episode,sex of patients,the nature(ischemia/hemorrhage) of stroke,the focal side(left/right hemisphere) of stroke and the death of stroke. METHODS:Totally 832 stroke patients who suffered from stroke for the first time were selected as the stroke group.Another 832 cases without signs and history of stroke were selected as control group and matched with the stroke group at the ratio of 1∶1 in birth year,age and sex.Birth date was recorded in solar calendar and in Chinese Stems and Branches calendar.The circular distribution method was used to statistically analyze the relation of birth date ranking with stroke frequency, age of episode,sex of patients,the nature,focal side and death of stroke. RESULTS:The frequency of stroke showed apparent central tendency in the patients who were born in all the 12 months of a year(r=-0.119 5,P< 0.001).There were 476 patients born in the season of winter monsoon(November to April of the next year) in the stroke group,but 417 patients in the control group,and there was significantly difference in the seasonal distribution between the two groups(P< 0.005).The episode age of stroke had the 4 lunar rhythm with a cycle of 4 months of birth,and the mean age was significantly different between the peak and the lowest values in the 4 month cycle(P< 0.001),and the peak and the lowest values was markedly different from those in the control group(P< 0.05).In the time series of the period of ten Heavenly Stems for the 10 days of birth,both male and female patients showed apparent central tendency(P< 0.005),and the difference between males and females was significant (P< 0.05),and significant differences between males or females of stroke group and control group were observed(P< 0.05).In the time series of the period of sixty pairs for the 60 days of birth,patients with ischemic or hemorrhagic stroke showed obvious central tendency,difference between ischemic and hemorrhagic stroke patients was significant(P< 0.005), and significant difference between ischemic or hemorrhagic stroke patients and control group was also observed(P< 0.01).In the time series of years of birth,patients with left or right focus changed regularly in a cycle of 4 years of birth.In the cycle,both the two kinds of stroke showed apparent central tendency,difference between the two kinds of stroke was significant(P< 0.005),difference between patients with left or right focus and the control group was observed(P< 0.05).There was no relationship of death of stroke patients with the birth date. CONCLUSION:Stroke patients are always born in the cold winter.The episode age of stroke patients changes regularly in a cycle of 4 months of birth.The sex of stroke patients is closely related with the period of ten Heavenly Stems for the 10 days of birth.The nature of stroke is closely related with the period of sixty pairs for the 60 days of birth.The focal side of stroke changes regularly in a cycle of 4 years of birth.
出处
《中国临床康复》
CAS
CSCD
2004年第19期3707-3709,共3页
Chinese Journal of Clinical Rehabilitation
基金
海南省重点科技计划项目(HN-2002-018)~~
