摘要
探讨应用生脉注射液治疗对正气虚衰为主的中晚期恶性肿瘤患者生存质量、肿瘤坏死因子的影响。将晚期恶性肿瘤患者随机分为两组 ,治疗组共 2 3例采用生脉注射液 (华西医科大学药厂生产 ) 3 0mL加入生理盐水 2 5 0mL中静脉滴入 ,每日 1次 ,2 0d为 1个疗程 ,对照组共 3 0例以能量合剂为主对症支持治疗 ,2 0d为 1个疗程 ,观察治疗前后患者体能状态卡氏 (KPS)评分和体质量变化、肿瘤坏死因子 -α(TNF α)变化。治疗组中 ,经生脉注射液治疗后比治疗前患者卡氏评分升高 ( 17/2 3 )占 73 9% ,体质量提高 ( 12 /2 3 )占 5 2 2 % ;TNF α下降 ( 16/2 3 )占 69 6% ;对照组则分别为 ( 7/3 0 ) 2 3 3 % ,( 4 /3 0 ) 13 3 % ,( 7/3 0 ) 2 3 3 % ,两组对比差异有统计学意义 ,P <0 0 0 1。生脉注射液治疗对改善晚期恶性肿瘤患者生存质量、抑制肿瘤恶病质的发生和进展有一定影响。
To study on the influence of existence quality and tumor necrosis factor in the patients who were suffered from malignant tumor diseases,and diagnosed according to the TCM type-deficiency of vital energy,all the patients were treated by Sheng Mai Injection.Twenty-three patients with malignant tumor diseases and lived in the late days were treated by Sheng Mai Injection,while with 30 patients in the control group were treated with normol methods.both the patients in the treatment group and in the control group were treated for 20 days.the KPS,the weight and TNF-α were observed before or after the treatment.Treated by Sheng Mai Injection,most of the patients state in the KPS to go up (17/23,73.9%) and the weight increases (12/23,52.2%) The TNF-α descent (16/23,69.6%); and in the control group were (7/30,23.3%),(4/30,13.3%),(7/30,23.3%) .which had aRemarkable differencer in the two groups,P<0.001.Treated by Sheng Mai Injection, the patients with malignant tumor diseases will have improvement of the existence quality and the progress of the tumor cachexia could be controlled.
出处
《肿瘤防治杂志》
2004年第6期652-653,共2页
China Journal of Cancer Prevention and Treatment
