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双紫汤治疗无排卵性不孕症76例临床研究 被引量:11

Clinical Research of "Shuangzi Decoction" in Treating Anovulatory Infertility in 76 Cases
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摘要 为观察双紫汤治疗肾虚型无排卵性不孕症的临床疗效并探讨其作用机理 ,将 10 8例患者随机分为两组 ,治疗组 76例 ,用双紫汤治疗 ;对照组 32例 ,用克罗米芬治疗。 3个月为 1个疗程 ,治疗 1~ 2个疗程。观察两组治疗前后促性腺激素、性激素、主卵泡直径的变化以及临床症状的改变。结果 :治疗组妊娠率为 6 3 15 % ,对照组为2 8 13% (P <0 0 1) ;治疗组排卵率为 80 2 6 % ,对照组为 81 2 5 % (P >0 0 5 )。两组血清促卵泡素 (FSH)、促黄体生成素 (LH)、雌二醇 (E2 )均较治疗前明显升高 (P <0 0 5 ) ,主卵泡直径明显增大 (P <0 0 5 )。提示补肾填精的双紫汤具有促排卵。 To observe the clinical effects and mechanism of 'Shuangzi Decoction' in the treatment of anovulatory infertility, 108 cases were randomized into two groups: treatment group in which 76 cases were treated by 'Shuangzi Decoction' and control group in which 32 cases were treated by clomiphene, with 3 months in a course and for 1-2 courses. The gonadotropic hormone, sex hormone, chief follicular diameter and clinical symptoms were observed before and after treatment. Results: The pregnancy rate was 63.16% in treatment group and 28.13% in control group (P<0.05); the ovulatory rate was 80.26% in treatment group and 81.25% in control group (P>0.05); in both groups, FSH, LH, E 2 and the follicular diameter increased obviously (P<0.05). It is indicated that 'Shuangzi Decoction' can promote the ovulation and elevate pregnancy rate.
出处 《上海中医药杂志》 北大核心 2004年第7期39-41,共3页 Shanghai Journal of Traditional Chinese Medicine
关键词 补肾填精 不孕症 肾虚 双紫汤 Nourishing kidneys and supplementing essence female infertility kidney asthenia Shuangzi Decoction
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参考文献4

  • 1中国中西医结合学会妇产科专业委员会第三届学术会议.女性不孕症的中西医结合诊疗标准[J].中西医结合杂志,1991,11(6):378-378.
  • 2中华人民共和国卫生部.中药新药治疗女性不孕症的临床研究指导原则[S].[S].,1993.276-278.
  • 3林金芳,于传鑫.排卵监测[J].上海医学,1992,15(2):110-114. 被引量:12
  • 4黄薇,曹泽毅,韩字研.克罗米芬对黄体功能的影响[J].中华妇产科杂志,1995,30(5):311-313. 被引量:13

二级参考文献2

  • 1叶尚勉,生殖与避孕,1989年,9卷,28页
  • 2Yuen B H,Fertil Steril,1988年,49卷,626页

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