摘要
为观察双紫汤治疗肾虚型无排卵性不孕症的临床疗效并探讨其作用机理 ,将 10 8例患者随机分为两组 ,治疗组 76例 ,用双紫汤治疗 ;对照组 32例 ,用克罗米芬治疗。 3个月为 1个疗程 ,治疗 1~ 2个疗程。观察两组治疗前后促性腺激素、性激素、主卵泡直径的变化以及临床症状的改变。结果 :治疗组妊娠率为 6 3 15 % ,对照组为2 8 13% (P <0 0 1) ;治疗组排卵率为 80 2 6 % ,对照组为 81 2 5 % (P >0 0 5 )。两组血清促卵泡素 (FSH)、促黄体生成素 (LH)、雌二醇 (E2 )均较治疗前明显升高 (P <0 0 5 ) ,主卵泡直径明显增大 (P <0 0 5 )。提示补肾填精的双紫汤具有促排卵。
To observe the clinical effects and mechanism of 'Shuangzi Decoction' in the treatment of anovulatory infertility, 108 cases were randomized into two groups: treatment group in which 76 cases were treated by 'Shuangzi Decoction' and control group in which 32 cases were treated by clomiphene, with 3 months in a course and for 1-2 courses. The gonadotropic hormone, sex hormone, chief follicular diameter and clinical symptoms were observed before and after treatment. Results: The pregnancy rate was 63.16% in treatment group and 28.13% in control group (P<0.05); the ovulatory rate was 80.26% in treatment group and 81.25% in control group (P>0.05); in both groups, FSH, LH, E 2 and the follicular diameter increased obviously (P<0.05). It is indicated that 'Shuangzi Decoction' can promote the ovulation and elevate pregnancy rate.
出处
《上海中医药杂志》
北大核心
2004年第7期39-41,共3页
Shanghai Journal of Traditional Chinese Medicine
关键词
补肾填精
不孕症
肾虚
双紫汤
Nourishing kidneys and supplementing essence
female infertility
kidney asthenia
Shuangzi Decoction