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腮腺多形性腺瘤生物学行为相关因素的研究 被引量:16

Study of the relative factors of the biological behavior of pleomorphic adenoma in parotid
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摘要 目的 研究腮腺多形性腺瘤的局部生长方式及其相关因素。方法 通过观察97例原发腮腺多形性腺瘤的组织切片,了解包膜受累发生率以及包膜外浸润的发生率及扩展范围,并通过肿瘤组织类型、各成分含量、体积、病程等与包膜浸润状况的相关关系的研究,探讨腮腺多形性腺瘤的局部生长方式及其相关因素。结果 上皮成分为主型伴细胞增生活跃者较黏液样成分为主、细胞增生不活跃型的包膜更易浸润或不完整。随着上皮成分的增加或黏液样成分的减少和病程的延长,包膜浸润或不完整的发生率增加。结论 腮腺多形性腺瘤的局部生长方式与其组织学类型、形态,各成分的相对含量及病程有相关性。 Objective To study the growth way of parotid pleomorphic adenoma and the relative factors. Methods The histological slides of 97 cases of the primary parotid pleomorphic adenoma were examined for the state of intra-capsule infiltration and extra-infiltration . The relative relationslips between the infiltration state and the histological type, relative amount of various components, size and course of the tumor were analysed to investigate the growth way and relative factors. Results 1. There were more chances to develop infiltration of tumor in which the major content was epithelium. The tumor was severer with the increasing of epithelium, and decreasing of mucous content and elongation of course of the disease. 2. The limitation of the extra-envelop infiltration and budding was 0.085 -0.210 mm,so, the boundary of partial parotidectomy should be away from the 1 cm envelop. Conclusion The growth way of parotid pleomorphic adenoma is related to the histological types and characters, relative amount of various components and the course of the tumor
出处 《中华口腔医学杂志》 CAS CSCD 北大核心 2004年第4期277-279,共3页 Chinese Journal of Stomatology
关键词 腮腺多形性腺瘤 生物学行为 相关因素 肿瘤生长 组织学类型 Parotid, neoplasms Adenoma, pleomorphic Biological behavior
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参考文献8

  • 1Palacios E, Valvassori G. Parotid mass: pleomorphic adenoma (mixed tumor). Ear Nose Throat J,1999,78: 746-747.
  • 2Junquera L, Alonso D, Sampedro A, et al. Pleomorphic adenoma of the salivary glands: prospective clinicopathologic and flow cytometric study. Head Neck, 1999, 21: 652-665.
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  • 8陆蔚人,方云鹤,平金良,莫晓东.腮腺多形性腺瘤包膜状况与临床的关系[J].口腔医学,1999,19(1):41-42. 被引量:20

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