摘要
目的 探讨善得定联合生大黄对重症急性胰腺炎的治疗价值。方法 将 5 1例重症急性胰腺炎患者随机分为三组 :A组 16例 ,为善得定联合生大黄治疗组 ;B组 15例 ,为善得定治疗组 ;C组 2 0例 ,为生大黄治疗组。观察患者治疗前和治疗后第 7天的APACHEⅡ评分及治疗后腹痛缓解时间 ,首次排便时间、并发症发生率及平均住院天数。并把患者中转手术或死亡归为内科治疗失败。结果 三组治疗失败率无显著差异 (P >0 0 5 )。C组并发症发生率明显高于A、B两组 (P <0 0 5 )。A组通便时间较B组早 ,差异有显著性 (P <0 0 0 1)。A组腹痛缓解时间及平均住院天数短于B、C两组 ,差异有显著性 (P <0 0 1)。治疗后 7天A、B两组APACHEⅡ评分较C组好 (P <0 0 5 )。结论 联合应用善得定和生大黄治疗重症急性胰腺炎有协同作用 。
Objective To study the therapeatic effect of combining sandostatin and rhubarb in treating severe acute pancreatitis(SAP). Methods 51 patients were randomly divided into three groups:group A,treated with sandostatin and rhubarb,n=16;group B,treated by sandostatin,n=15;group C, treated with rhubarb,n=20.APACHEⅡscore, clinical symptoms, the incidence of complication and average hospitalization days were observed and recorded.Chi-square test and t test were used in statistical analysis.Results There was no significant difference (P>0.05) in the rate of therapeutic failure among three groups.The time for first stool was significantly shorter in group A than that in group B (P<0.001) .The times of abdominal pain relief and average hospitalization day were significantly in group A (P<0.01) than that in group B and group C.APACHEⅡscore of 7 days after treatment was significantly lower in group A and group B than that in group C (P<0.05).Conclusion The therapeutic effect of combining sandostatin with rhubarb in treatment of severe acute pancreatitis is superior to western medicine or Chinese medicine alone.
出处
《中华急诊医学杂志》
CAS
CSCD
2004年第7期468-469,共2页
Chinese Journal of Emergency Medicine
