摘要
目的 探讨应用中药肺积方与放射性12 5I粒子植入结合治疗晚期非小细胞肺癌的疗效和方法。方法 治疗组 10例晚期肺癌患者行放射性12 5I粒子肿瘤内植入治疗 ,植入当天起采用中药肺积方口服。每日 1剂 ,30d为 1个疗程 ;治疗 1个月后复查 ,观察治疗前后生活质量、主要症状改善情况及肿瘤控制情况 ,追踪生存期。结果 治疗后比治疗前大部分 (80 %以上 )患者KPS评分和体质量稳定或提高 ;疲乏、纳差、疼痛等主要症状改善 ;肿瘤控制情况 :CR 1例 ,PR 5例 ,SD 3例 ,PD 1例。(CR +PR)共 6例 ,治疗总有效率为 6 0 % ,稳定率为 30 % ,进展率为10 %。中位生存期 11个月。 1年生存率 5 0 %。结论 中药肺积方与12 5I粒子植入结合治疗中晚期非小细胞肺癌对改善患者生活质量和主要症状、控制肿瘤的增长、延长生存期均有较好疗效。
Objective It is to discuss the curative effect and method of Feijifang and radioactivity*' 125 I particles implanted on non-small cell lung cancer at later period.Methods Ten patients with lung cancer at later period were treated with Feijifang and radioactivity*' 125 I particles implanted. After being treated for one month, the live quality, the main symptom improving situation and the tumor controlling situation were observed and the existent time was tracked before and after treatment.Results The KPS marks and body masses of most patients (more 80%) were stabilization or enhanced after treatment than those before treatment. The main symptom just as lassitude, no appetite, pain and so on was improved. The tumor controlling situation was that CR was one case, PR was five cases, SD was three cases and PD was one case. CR and PR were six cases and the total effective rate was 60%. The stabilization rate was 30%. The progression rate was 10%. The median existent time was eleven months. The one year existent rate was 50%.Conclusion Feijifang and*' 125 I particle implanted have better curative effect on improving the live quality and the main symptom, controlling the tumor growing and prolonging the existent time in treating the patients with non-small cell lung cancer diseases.
出处
《现代中西医结合杂志》
CAS
2004年第15期1974-1976,共3页
Modern Journal of Integrated Traditional Chinese and Western Medicine
