摘要
目的 应用磁共振相位对比法 ,观察ChiariⅠ畸形合并脊髓空洞病人脑脊液的流动情况 ,并进行定量分析。方法 对 14例ChiariⅠ畸形合并脊髓空洞患者及 14例正常成人进行矢状位扫描 ,在正中矢状位上测量延前池及C2 3水平蛛网膜下腔腹背侧宽径 ;并对其中 10例患者及 10例正常成人应用磁共振相位对比序列 ,配合以回顾性心电门控技术 ,分别测量中脑导水管、枕大孔区、C2 3间盘水平各层面脑脊液流速。结果 与对照组比较 ,合并空洞的ChiariⅠ畸形患者延前池及颈椎蛛网膜下腔均变窄 (P <0 .0 5 ) ;中脑导水管足向CSF最大流速增大 (P <0 .0 5 ) ,头向CSF最大流速明显增大 (P <0 .0 1) ;枕大孔区足向及头向CSF最大流速较对照组明显增大 (P <0 .0 1) ;C2 3间盘水平足向CSF最大流速明显增大 (P <0 .0 1) ,头向CSF最大流速与对照组比较无明显差异 (P >0 .0 5 ) ;患者的R R间期较对照组缩短 (P <0 .0 5 )。结论 ChiariⅠ畸形合并脊髓空洞患者的脑脊液流动增强 ,推测对空洞的形成可能起重要的作用。
Objective To quantitatively study the features of cerebrospinal fluid flow dynamics in Chiari Ⅰ malformation with syrinx by using phase-contrast MRI. Methods Fourteen patients and fourteen healthy subjects underwent sagittal MR scan. To measure lengths of prebulbar cistern and ventral and dorsal spinal subarachnoid spaces at the C2-3 level. Among these subjects,ten patients and ten healthy subjects underwent retrospectively gated phase-contrast MRI scan. Velocities were measured at three regions of interest:aqueduct, ventral foramen magnum and ventral spinal subarachnoid spaces at the C2-3 level. Results The lengths in patients were significantly decreased compared with these in healthy subjects ( P < 0.05 ). The increased systolic velocity ( P <0.05) and diastolic velocity ( P <0.01) of aqueduct were identified;the systolic velocity and diastolic velocity of ventral foramen magnum increased distinctly ( P <0.01);the systolic velocity of C2-3 level increased significantly ( P <0.01),while the diastolic velocity was unaltered. Decreased R to R interval in patients was also demonstrated ( P <0.05). Conclusion Cerebrospinal fluid flow was enhanced in Chiari Ⅰ malformation with syrinx,which was supposed to facilitate the development of syrinx.
出处
《中国医学影像技术》
CSCD
2004年第7期985-988,共4页
Chinese Journal of Medical Imaging Technology
基金
教育部教育振兴行动计划特殊专项(985工程学科建设项目)资助
