摘要
目的探讨急性胰腺炎死后不同时间眼玻璃体液淀粉酶变化。方法用1%牛胆酸钠诱导家兔急性胰腺炎动物模型建立,于死后不同时间和正常对照组,观察其淀粉酶变化。结果家兔急性胰腺炎死后72h眼玻璃体液淀粉酶含量(x)与死亡时间(y)存在相关关系,并导出其二项式回归方程为y=8.7420+0.7699x-0.0083x2(R2=92.62792,F=14.89734,P=0.001)。可作为推定早期损伤时间的参考指标。结论家兔急性胰腺炎死后不同时间眼玻璃体液淀粉酶改变为法医早期死亡时间推断提供了灵敏客观的实验依据。
Objective To investigate concentration changes of amylase in rabbits vitreous humor of acute pancreatitis associated with postmortem different interval.Methods To induce animal model of acute pan-creatitis with sodium taurocholate,observed concentration changes of amylase after different postmortem in-terval,then compared with normal.Results The concentration of amylase in vitreous humor of rabbit24h after death were related to postmortem interval significantly;The concluded formulae of the relationship between postmortem interval and amylase concentration is y=8.7420+0.7699x-0.0083x2(R2=92.62792,F=14.89734,P=0.001).Conclusion Concentration changes of amylase in vitreous humor of acute pancreatitis associated with postmortem interval may provide a new sensitive and objective method for the forensic early injury time estimation.
出处
《法医学杂志》
CAS
CSCD
2004年第3期143-144,共2页
Journal of Forensic Medicine
基金
温州市科委立项并资助研究项目(S2002A071)
