摘要
目的 :研究 1999年 9月~ 2 0 0 2年 9月伏牛山东南麓地区门诊原发性高血压 (EH)及相关疾病患者的主要病因及靶器官损害程度等多项流行病学指标构成情况。方法 :按照 1999年WHO/ISH及《中国高血压防治指南》标准进行分类、分级和危险分层 ,研究数据由SPSS10 .0软件包处理。结果 :74 1例EH患者 (平均年龄5 2 .5± 5 .6岁 ,男女之比为 1∶1.16 ) ;1级 3.37% ;2级 19.70 % ;3级 76 .92 %。有家族史者 5 0 .74 % ,有吸烟史6 9.6 8% ,有饮酒史 6 3.85 % ,食盐量 >10g/d者 85 .83% ,超重与肥胖者 74 .5 0 % ,危险分层 :低危组 2 .5 6 % ,中危组2 0 .11% ,高危组 32 .5 2 % ,极高危组 4 6 .2 9%。心血管疾病 4 5 .75 % ,脑血管病 31.98% ,肾功能不全或衰竭者2 1.73% ;EH伴糖尿病者 10 .39%。血管疾病 :腹主动脉夹层 0 .14 % ,症状性动脉疾病 33.6 0 % ,眼底动脉出血或渗血、视神经乳头水肿 17.14 % ,心脑肾均有明显病变者 2 1.19%。结论 :吸烟、饮酒、高钠饮食、超重、遗传是EH的主要危险因素 ,而高血压又是心、脑、肾等靶器官受损的主要危险因素。积极开展高血压三级预防是EH防治工作的重要环节 。
Objective:To investigate the proportionate rate of the epidemiologic measures on the main etiology and target organ damage of essential hypertension (EH) and related diseases among the patients.Method:To categorize EH patients along with risk stratification according to (The Guideline for the prevention and treatment of hypertension in China)(1999). The research data were managed with software package SPSS 10.0.Result:Totally 741 EH patients in average Age 52.5± 5.6 years; M vs F=1∶ 1.16; Class Ⅰ 3.37%, Class Ⅱ 19.70%, Class Ⅲ 76.92%;Family history: positive 50.74%, negative 24.43%, unknown 24.83%; History of smoking 69.68%; History of alcohol drinking 63.85%; Salt intake >10 g/d 85.83%; BMI overweight and obesity 74.49%; Risk stratification: low risk 2.56%, medium risk 20.11%, high risk 32.52% and very high risk 46.29%; CVD 45.75%; Cerebrovascular disease 31.98% (among them, ischemic stroke 54.43%, hemorrhagic stroke 15.61 and TIA 29.96%); Renal insufficiency and renal failure 21.73%. EH accompanied with diabetes mellitus 10.39%, vascular diseases (dissection of abdominal aorta 0.14%, symptomatic arteriosclerosis 33.60%, retinal hemorrage or ecchymosis of fundus arteries and papilloedema of disk 17.14%). 21.19% patients simultaneously had remarkable damage of heart, brain and kidney.Conclusion: Smoking, alcohol drinking, high dietary salt intake, overweight and heredity are the main risk factors of EH which turns to be the principal risk factor causing the target organ damage on heart, brain and kidney.
出处
《临床心血管病杂志》
CAS
CSCD
北大核心
2004年第7期414-415,共2页
Journal of Clinical Cardiology
关键词
高血压
流行病学研究
Hypertension
Epidemiologic study