摘要
目的 :观察丹皮酚的镇痛作用。方法 :采用醋酸扭体法和热板法观察丹皮酚的镇痛作用。结果 :小鼠连续 3天灌胃给予丹皮酚 5 0 .2 7mg/kg、2 5 .14mg/kg和 12 .5 7mg/kg ,均能明显减少醋酸所致小鼠的扭体反应次数 ,使热刺激所致小鼠疼痛的痛阈值明显提高。结论
Objective:To observe the analgesic effect of Paeonal. Methods: Hot plate test and the acetic acid writhing test are used in mice. Results: Paeonal at the doses of 50.27mg/kg、25.14mg/kg and 12.57mg/kg can inhibit the writhing response induced by acetic acid and can markedly raise pain-threshold induced by heat stimulation in mice. Conclusion: Paeonal has analgesic action .
出处
《包头医学院学报》
CAS
2004年第2期99-100,共2页
Journal of Baotou Medical College
关键词
丹皮酚
镇痛作用
药理学
痛阈值
Paeonal
Acetic acid writhing test
Hot plate test
Analgesia
