摘要
目的 :观察复方七叶皂苷凝胶治疗急性软组织挫伤的疗效 ,并与双氯芬酸凝胶比较。方法 :2 2 9例急性软组织挫伤病人 ,男性 16 9例 ,女性 6 0例 ,年龄 (32±s 14 )a ,14～ 72a ,分成 2组。治疗组12 8例 ,于受伤部位涂抹复方七叶皂苷凝胶 ,bid ;对照组 10 1例 ,于受伤部位涂抹双氯芬酸凝胶 ,bid。 2组疗程均为 7d ,分别观察 2组病人用药前后疼痛、肿胀、红热、功能障碍等症状体征。结果 :治疗组显效率 81.2 % (10 4 / 12 8) ,总有效率 93.0 % (119/12 8) ,对照组显效率 9.9% (10 / 10 1) ,总有效率82 .2 % (83/ 10 1)。 2组疗效差异有非常显著意义(P <0 .0 1)。结论 :复方七叶皂苷凝胶外用治疗急性软组织挫伤疗效显著 ,优于双氯芬酸凝胶。
AIM: To observe the efficacy of compound aescin gel in treating acute soft tissue contusion and compared with diclofenac. METHODS: Two hundred and twenty-nine patients (M 169, F 60;age (32± s 14) a) with acute soft tissue contusion were divided into two groups. Treatment group of 128 patients (M 96,F 32;age (31±14)a) was coated with compound aescin gel,bid,for 7 d. Control group of 101 patients (M 73,F 28;age (34±15)a) was coated with diclofenac gel,bid,for 7 d . Symptoms of pain,tumidity,fever and functional disorders before and after treatment were observed. RESULTS: The total effective rate was 93.0 % in treatment group,and 82.2 % in control group. The obvious effective rate was 81.2 % in treatment group,and 9.9 % in control group. There was a significant difference in treatment effect between the two groups( P <0.01 ). CONCLUSION: Compound aescin gel is a safe and effective drug in treatment of acute soft tissue contusion and is superior to diclofenac.
出处
《中国新药与临床杂志》
CAS
CSCD
北大核心
2004年第7期395-397,共3页
Chinese Journal of New Drugs and Clinical Remedies
