摘要
目的 了解沈阳地区一般人群血清和脐带血中全氟辛烷磺酸 (PFOS)和全氟辛酸 (Perfluorooctanoicacid,PFOA)污染现状。方法 采用液相色谱 质谱仪联机选择性监测离子法 (PFOS :m z =4 99,PFOA :m z =4 1 3) ,测定脐带血和被调查者血清中PFOS和PFOA浓度。结果 男女血清中PFOS和PFOA浓度几何均数分别为 4 0 73μg L和 4 5 4 6 μg L、1 1 5 3μg L和 8 97μg L- 1 。脐带血中PFOS和PFOA浓度几何均数分别为2 2 1 4 μg L和 0 2 6 4 μg L。成人血清和脐带血中PFOS和PFOA浓度与年龄无关相关性 (p <0 0 5 )。 结论 一般人群体内也存在PFOS污染物 ,而且血清PFOS浓度高于美国人和日本人水平。
Objective To study the status of perfluorooctane sulfonate (PFOS), and Perfluorooctanoic acid(FOA) pollution in serum and umbilical blood among general people in Shenyang area.Methods concentration of PFOS and PFOA in adult serum and umbilical blood samples was measured by means of liquid phase chromatography/mass spectrograph selective iron monitoring(PFOS:m/z=499, PFOA:m/z=413). Results It was showed that geometric mean of serum concentration of PFOS of male was 40 73μg/L and that of female was 45 46μg/L, PFOA is 11 53μg/L and 8 97μg/L. Geometric mean concentration of PFOS and PFOA in umbilical blood was 2 214μg/L and 0 264μg/L There was no correlativity between concentration of PFOS, PFOA and age in adult serum and umbilical blood. Conclusion It was suggested that there was PFOS contamination in common group in Shenyang. Also, fetus was exposed in PFOS and PFOA during its embryonic period. There were also PFOS and PFOA pollution in human umbilical blood samples.
出处
《卫生研究》
CAS
CSCD
北大核心
2004年第4期481-483,共3页
Journal of Hygiene Research
基金
20 0 2年度日本国际协力事业团 (JICA)资助项目
关键词
体氟辛炕磺酸
全氟辛酸人类
血清
脐带血
perfluorooctane sulfonate, perfluorooctanoic acid, umbilical blood
